Evidence map›Paper›PMID 39456167›Full record

ArticleBiomolecules2024

Isorhamnetin Alleviates Renal Fibrosis by Inducing Endogenous Hydrogen Sulfide and Regulating Thiol-Based Redox State in Obstructed Kidneys.

Zhen Zhang, Haiyan Zhang, Jianyu Shi, Zheng Wang, Yanni Liang, Jingao Yu, Hongbo Wang, Zhongxing Song, Zhishu Tang, Dongbo Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Prunin: An Emerging Anticancer Flavonoid.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhen ZhangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Haiyan ZhangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Jianyu ShiShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Zheng WangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Yanni LiangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Jingao YuShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Hongbo WangDepartment of the Thyroid and Breast Surgery, Xianyang Central Hospital, Xianyang 712000, China.
Zhongxing SongShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Zhishu TangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Dongbo ZhangShaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Jian YaoDivision of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo 409-3898, Japan.ORCID 0000-0003-2622-0215

Funding

Chunhui Cooperative scientific research project of Ministry of Education 201900105Collaborative Innovation Projects of Education Department of Shaanxi Provincial Government 21JY012General projects of Shaanxi Province Science and Technology Department 2021SF-368Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources 2060302Natural Science Foundation of China 82104512
6 · The paper itself

Abstract

Isorhamnetin (ISO) is an active flavonoid compound mainly isolated from the fruits of

Indexed as

FibrosisHydrogen SulfideQuercetinAnimalsCystathionine beta-SynthaseEpithelial-Mesenchymal TransitionKelch-Like ECH-Associated Protein 1KidneyKidney DiseasesMaleNF-E2-Related Factor 2Oxidation-ReductionOxidative StressRatsRats, Sprague-DawleySulfhydryl Compounds3-methylquercetinCystathionine beta-SynthaseHydrogen SulfideKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2QuercetinSulfhydryl CompoundsTransforming Growth Factor beta1hydrogen sulfideisorhamnetinkeap1renal fibrosissulfhydration

Identifiers

PMID39456167
PMCPMC11506782

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.