Evidence map›Paper›PMID 39456449›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Prevention of Sunlight-Induced Cell Damage by Selective Blue-Violet-Light-Filtering Lenses in A2E-Loaded Retinal Pigment Epithelial Cells.

Coralie Barrau, Mélanie Marie, Camille Ehrismann, Pauline Gondouin, José-Alain Sahel, Thierry Villette, Serge Picaud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Coralie BarrauR&D Essilor International, 147 Rue de Paris, 94220 Charenton-Le-Pont, France.
Mélanie MarieInstitut de la Vision, French National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Sorbonne Université, 75012 Paris, France.ORCID 0000-0003-3516-3582
Camille EhrismannR&D Essilor International, 147 Rue de Paris, 94220 Charenton-Le-Pont, France.
Pauline GondouinInstitut de la Vision, French National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Sorbonne Université, 75012 Paris, France.
José-Alain SahelInstitut de la Vision, French National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Sorbonne Université, 75012 Paris, France.
Thierry VilletteR&D Essilor International, 147 Rue de Paris, 94220 Charenton-Le-Pont, France.
Serge PicaudInstitut de la Vision, French National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Sorbonne Université, 75012 Paris, France.ORCID 0000-0002-0548-5145

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI John D Ash · 1989 to 2026
$17.8M
Agence Nationale de la Recherche, FOReSIgGHT ANR-18-IAHU-0001Agence Nationale de la Recherche, LABEX LIFESCIENCES ANR-10-LABX-0065Essilor NANEI NIH HHS P30 EY008098NIH HHS P30 EY08098Research to Prevent Blindness unrestricted
6 · The paper itself

Abstract

Blue light accelerates retinal aging. Previous studies have indicated that wavelengths between 400 and 455 nm are most harmful to aging retinal pigment epithelia (RPE). This study explored whether filtering these wavelengths can protect cells exposed to broad sunlight. Primary porcine RPE cells loaded with 20 µM A2E were exposed to emulated sunlight filtered through eye media at 1.8 mW/cm

Indexed as

blue-violet lightfilteroxidative stressphotoprotection

Identifiers

PMID39456449
PMCPMC11504362

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.