The Protective Effect of the Supplementation with an Extract from

Agnieszka Ruczaj, Joanna Rogalska, Małgorzata Gałażyn-Sidorczuk, Małgorzata M Brzóska

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Neurotoxic mechanisms of cadmium in neurodegenerative diseases.Frontiers in cell and developmental biology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Agnieszka RuczajDepartment of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222 Bialystok, Poland.ORCID 0000-0003-0259-8344

Joanna RogalskaDepartment of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222 Bialystok, Poland.

Małgorzata Gałażyn-SidorczukDepartment of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222 Bialystok, Poland.

Małgorzata M BrzóskaDepartment of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222 Bialystok, Poland.ORCID 0000-0002-3023-0056

Funding

Medical University of Bialystok (Poland) B.SUB.24.115Medical University of Bialystok (Poland) N/ST/ZB/18/002/2221Medical University of Bialystok (Poland) SUB/2/DN/21/001/2221Medical University of Bialystok (Poland) SUB/2/DN/22/003/2221National Science Centre (Poland) N N405 051140

6 · The paper itself

Abstract

Since even low-level environmental exposure to cadmium (Cd) can lead to numerous unfavourable health outcomes, including damage to the nervous system, it is important to recognize the risk of health damage by this xenobiotic, the mechanisms of its toxic influence, and to find an effective protective strategy. This study aimed to evaluate, in a female Wistar rat model of current human environmental exposure to Cd (1 and 5 mg/kg of diet for 3-24 months), if the low-to-moderate treatment with this element can harm the brain and whether the supplementation with a 0.1%

Indexed as

BiomarkersBrainCadmiumFruitPhotiniaPlant ExtractsRats, WistarAnimalsDietary SupplementsDisease Models, AnimalFemaleHumansNeurotoxicity SyndromesRatsBiomarkersCadmiumPlant Extractsacetylcholinesterase (AChE)adenosine triphosphatase (ATPase)Aronia melanocarpa L. berries extract (AE)calmodulin (CAM)markers of neurotoxicitymetalloproteinases and their tissue inhibitors (MMPs and TIMPs)nervous tissuenitric oxide synthase 1polyphenolic compoundsprotection from cadmium neurotoxicity

Identifiers

PMID39456671

DOI10.3390/ijms252010887

PMCPMC11507053

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.