Evidence map›Paper›PMID 39456762›Full record

ArticleInternational journal of molecular sciences2024

The Composition of the HDL Particle and Its Capacity to Remove Cellular Cholesterol Are Associated with a Reduced Risk of Developing Active Inflammatory Rheumatoid Arthritis.

Marcia Benacchio Giacaglia, Vitoria Pires Felix, Monique de Fatima Mello Santana, Leonardo Szalos Amendola, Perola Goberstein Lerner, Sibelle D Elia Fernandes, Cleber Pinto Camacho, Marisa Passarelli

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcia Benacchio GiacagliaPrograma de Pós-Graduação em Medicina, Universidade Nove de Julho (UNINOVE), Sao Paulo 01525-000, Brazil.
Vitoria Pires FelixLaboratório de Lípides (LIM10), Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo 01246-000, Brazil.
Monique de Fatima Mello SantanaLaboratório de Lípides (LIM10), Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo 01246-000, Brazil.
Leonardo Szalos AmendolaLaboratório de Lípides (LIM10), Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo 01246-000, Brazil.
Perola Goberstein LernerDepartamento de Reumatologia, Hospital do Servidor Público Municipal (HSPM), Sao Paulo 01532-000, Brazil.
Sibelle D Elia FernandesLaboratório de Análise Clínicas, Hospital do Servidor Público Municipal (HSPM), Sao Paulo 01532-000, Brazil.
Cleber Pinto CamachoPrograma de Pós-Graduação em Medicina, Universidade Nove de Julho (UNINOVE), Sao Paulo 01525-000, Brazil.ORCID 0000-0002-8653-0031
Marisa PassarelliPrograma de Pós-Graduação em Medicina, Universidade Nove de Julho (UNINOVE), Sao Paulo 01525-000, Brazil.ORCID 0000-0002-9249-4698

Funding

Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior CAPES, 33002010062P5 to DSR and LSAFundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP 2016/15603-0 to MP; 2022/11186-7 to DSR; 2021/02401-9 to MFMS
6 · The paper itself

Abstract

In rheumatoid arthritis (RA), the risk of cardiovascular death is 50% higher compared to the general population. This increased risk is partly due to the systemic inflammation characteristic of RA and changes in the lipoprotein profiles. This study investigated plasma lipid levels, lipid ratios, and the composition and functionality of high-density lipoprotein (HDL) in control individuals and RA subjects based on the disease's inflammatory score (DAS28). This study included 50 control (CTR) individuals and 56 subjects with RA, divided into remission/low-activity disease (DAS28 < 3.2;

Indexed as

Arthritis, RheumatoidCholesterolAdultAgedApolipoprotein A-IApolipoproteins BCase-Control StudiesCholesterol, HDLFemaleHumansInflammationLipoproteins, HDLMacrophagesMaleMiddle AgedTriglyceridesApolipoprotein A-IApolipoproteins BCholesterolCholesterol, HDLLipoproteins, HDLTriglyceridesatherosclerosischolesterol effluxHDLinflammationrheumatoid arthritis

Identifiers

PMID39456762
PMCPMC11507075

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.