Evidence mapPaperPMID 39456775Full record

SynthesisInternational journal of molecular sciences2024

The Association and Prognostic Implications of Long Non-Coding RNAs in Major Psychiatric Disorders, Alzheimer's Diseases and Parkinson's Diseases: A Systematic Review.

Lin Zhu, Meng Guo, Ke Li, Chuang Guo, Kuanjun He

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Special Issue "Molecular Underpinnings of Schizophrenia Spectrum Disorders".International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lin ZhuCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao 028000, China.
Meng GuoFinance Office, Inner Mongolia Minzu University, Tongliao 028000, China.
Ke LiCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao 028000, China.
Chuang GuoCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao 028000, China.
Kuanjun HeCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao 028000, China.ORCID 0009-0005-4220-7186

Funding

the Natural Science Foundation of Inner Mongolia Autonomous Region 2023MS08024the Natural Science Foundation of Inner Mongolia Autonomous Region 2024LHMS08003the Natural Science Foundations of China 82060256
6 · The paper itself

Abstract

The prevalence of psychiatric disorders and neurodegenerative diseases is steadily increasing, placing a significant burden on both society and individuals. Given the intricate and multifaceted nature of these diseases, the precise underlying mechanisms remain elusive. Consequently, there is an increasing imperative to investigate the mechanisms, identify specific target sites for effective treatment, and provide for accurate diagnosis of patients with these diseases. Numerous studies have revealed significant alterations in the expression of long non-coding RNAs (lncRNAs) in psychiatric disorders and neurodegenerative diseases, suggesting their potential to increase the probability of these diseases. Moreover, these findings propose that lncRNAs could be used as highly valuable biomarkers in diagnosing and treating these diseases, thereby offering novel insights for future clinical interventions. The review presents a comprehensive summary of the origin, biological functions, and action mechanisms of lncRNAs, while exploring their implications in the pathogenesis of psychiatric disorders and neurodegenerative diseases and their potential utility as biomarkers.

Indexed as

Alzheimer DiseaseBiomarkersMental DisordersParkinson DiseaseRNA, Long NoncodingHumansPrognosisBiomarkersRNA, Long NoncodingbiomarkerslncRNAneurodegenerative diseasespathogenesispsychiatric disorders

Identifiers

PMID39456775
PMCPMC11507000

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.