Evidence map›Paper›PMID 39456843›Full record

ArticleInternational journal of molecular sciences2024

Variants rs3804099 and rs3804100 in the

Julio Flores-González, Zurisadai Monroy-Rodríguez, Ramcés Falfán-Valencia, Ivette Buendía-Roldán, Ingrid Fricke-Galindo, Rafael Hernández-Zenteno, Ricardo Herrera-Sicairos, Leslie Chávez-Galán, Gloria Pérez-Rubio

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. TLR2 variants andUpsala journal of medical sciences · 2025
    Pooled it
  2. The role of TLRs (microbe recognition receptor) in gastric cancer: An update.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  3. Analyses of haplotypes ofFrontiers in genetics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julio Flores-GonzálezLaboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 14080, Mexico.ORCID 0000-0003-4707-718X
Zurisadai Monroy-RodríguezHLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Ramcés Falfán-ValenciaHLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0001-6877-8124
Ivette Buendía-RoldánTranslational Research Laboratory on Aging and Pulmonary Fibrosis, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-2825-506X
Ingrid Fricke-GalindoHLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0003-2132-1076
Rafael Hernández-ZentenoCOPD Clinic, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Ricardo Herrera-SicairosLaboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 14080, Mexico.
Leslie Chávez-GalánLaboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-2334-0361
Gloria Pérez-RubioHLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-6876-1012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to identify in patients with severe COVID-19 and acute respiratory distress syndrome (ARDS) the association between rs3804099 and rs3804100 (

Indexed as

COVID-19CytokinesSARS-CoV-2Spike Glycoprotein, CoronavirusToll-Like Receptor 2AdultAgedAllelesFemaleGenotypeHumansLeukocytes, MononuclearMaleMiddle AgedPolymorphism, Single NucleotideRespiratory Distress SyndromeCytokinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2TLR2 protein, humanToll-Like Receptor 2COVID-19genetic variantsrs3804100rs380499SARS-CoV-2TLR-2

Identifiers

PMID39456843
PMCPMC11507191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.