Evidence map›Paper›PMID 39456869›Full record

ArticleInternational journal of molecular sciences2024

Melatonin Mediates Cardiac Tissue Damage under Septic Conditions Induced by Lipopolysaccharide.

Milan Lazarević, Miloš Kostić, Tanja Džopalić, Danka Sokolović, Zorica Lazarević, Jelena Milovanović, Vanja Ničković, Dušan Sokolović

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Milan LazarevićDepartment of Immunology, Medical Faculty of Niš, University of Nis, 18000 Niš, Serbia.ORCID 0000-0001-8898-948X
Miloš KostićDepartment of Immunology, Medical Faculty of Niš, University of Nis, 18000 Niš, Serbia.
Tanja DžopalićDepartment of Immunology, Medical Faculty of Niš, University of Nis, 18000 Niš, Serbia.ORCID 0000-0003-1074-8592
Danka SokolovićBlood Transfusion Institute Niš, 18000 Niš, Serbia.
Zorica LazarevićClinic for Cardiovascular and Transplant Surgery, University Clinical Centre of Nis, 18000 Niš, Serbia.
Jelena MilovanovićFaculty of Medicine, Unisversity of Priština, 38220 Kosovska Mitrovica, Serbia.
Vanja NičkovićClinic of Gastroenterohepatology, University Clinical Centre of Niš, 18000 Niš, Serbia.
Dušan SokolovićInstitute for Biochemistry, Faculty of Medicine, University of Niš, 18000 Niš, Serbia.ORCID 0000-0001-6586-6428

Funding

Ministry of Education, Science, and Technological Development of the Republic of Serbia 451-03-65/2024-03/200113
6 · The paper itself

Abstract

Lipopolysaccharide (LPS) is known to induce oxidative stress and inflammation, leading to significant damage in cardiac tissues. This study investigates the protective effects of melatonin (MLT) against LPS-induced oxidative damage, inflammation, and apoptosis in rat heart tissue. Rats were divided into four groups (

Indexed as

ApoptosisLipopolysaccharidesMelatoninMyocardiumNitric Oxide Synthase Type IIOxidative StressAnimalsAntioxidantsCaspase 3Caspase 9InflammationInterleukin-6MaleNitric OxideRatsRats, WistarAntioxidantsCaspase 3Caspase 9Interleukin-6LipopolysaccharidesMelatoninNitric OxideNitric Oxide Synthase Type IIThiobarbituric Acid Reactive Substancesheartinflammationlipopolysaccharidemelatonin

Identifiers

PMID39456869
PMCPMC11508384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.