Evidence map›Paper›PMID 39456887›Full record

ArticleInternational journal of molecular sciences2024

Multi-Omics Analysis Identified Drug Repurposing Targets for Chronic Obstructive Pulmonary Disease.

Fang Wang, Carlos A Barrero

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. The Evolving Landscape of COPD Typization.Medicina (Kaunas, Lithuania) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fang WangDepartment of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19140, USA.ORCID 0000-0001-9898-0665
Carlos A BarreroDepartment of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19140, USA.ORCID 0000-0001-5779-6642

Funding

Flight Attendant Medical Research Institute YFAC142023
6 · The paper itself

Abstract

Despite recent advances in chronic obstructive pulmonary disease (COPD) research, few studies have identified the potential therapeutic targets systematically by integrating multiple-omics datasets. This project aimed to develop a systems biology pipeline to identify biologically relevant genes and potential therapeutic targets that could be exploited to discover novel COPD treatments via drug repurposing or

Indexed as

Drug RepositioningPulmonary Disease, Chronic ObstructiveComputational BiologyGenomicsHumansMultiomicsProteomeReceptors, G-Protein-CoupledSmad3 ProteinTissue Inhibitor of Metalloproteinase-1TranscriptomeProteomeReceptors, G-Protein-CoupledSmad3 ProteinSMAD3 protein, humanTIMP1 protein, humanTissue Inhibitor of Metalloproteinase-1bioinformaticschronic obstructive pulmonary diseasedrug repurposingmulti-omics data integrationsystems biology

Identifiers

PMID39456887
PMCPMC11507528

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.