Evidence map›Paper›PMID 39457020›Full record

ReviewInternational journal of molecular sciences2024

The Role of Tumor Biomarkers in Tailoring the Approach to Advanced Ovarian Cancer.

Noemi Tonti, Tullio Golia D'Augè, Ilaria Cuccu, Emanuele De Angelis, Ottavia D'Oria, Giorgia Perniola, Antonio Simone Laganà, Andrea Etrusco, Federico Ferrari, Stefania Saponara and 3 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. The -124C>T Mutation of theCurrent oncology (Toronto, Ont.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Noemi TontiDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0009-0006-3503-5010
Tullio Golia D'AugèDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1018-3088
Ilaria CuccuDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Emanuele De AngelisDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0009-0009-9930-2810
Ottavia D'OriaObstetrics and Gynecological Unit, Department of Woman's and Child's Health, San Camillo-Forlanini Hospital, 00152 Rome, Italy.
Giorgia PerniolaDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0321-9828
Antonio Simone LaganàUnit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-1543-2802
Andrea EtruscoUnit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7414-4224
Federico FerrariDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-7065-2432
Stefania SaponaraDivision of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-1022-0958
Violante Di DonatoDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-9254-5790
Giorgio BoganiGynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Andrea GianniniUnit of Gynecology, Department of Surgical and Medical Sciences and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0002-4388-0082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence has demonstrated the role of mutations of tumor biomarkers in diagnosing and treating epithelial ovarian cancer. This review aims to analyze recent literature on the correlation between tumor biomarkers and chemotherapy in nonmucinous ovarian cancer, providing suggestions for personalized treatment approaches. An extensive literature search was conducted to identify relevant studies and trials.

Indexed as

Biomarkers, TumorOvarian NeoplasmsBRCA1 ProteinBRCA2 ProteinCarcinoma, Ovarian EpithelialFemaleHumansMutationPoly(ADP-ribose) Polymerase InhibitorsPrecision MedicineBiomarkers, TumorBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinPoly(ADP-ribose) Polymerase InhibitorsBRCAgynecologic oncologyHRDmolecular classificationovarian cancerParpitarget therapies

Identifiers

PMID39457020
PMCPMC11508316

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.