Evidence map›Paper›PMID 39457074›Full record

ArticleInternational journal of molecular sciences2024

6-Gingerol Inhibits De Novo Lipogenesis by Targeting Stearoyl-CoA Desaturase to Alleviate Fructose-Induced Hepatic Steatosis.

Pan Li, Tingting Wang, Hongmei Qiu, Ruoyu Zhang, Chao Yu, Jianwei Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Jiangtang Decoction for Type 2 Diabetes and NAFLD: Integrative AnalysisEndocrine, metabolic & immune disorders drug targets · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pan LiChongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Medical University, Chongqing 400016, China.
Tingting WangChongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Medical University, Chongqing 400016, China.
Hongmei QiuCollege of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ruoyu ZhangChongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing Medical University, Chongqing 400016, China.
Chao YuChongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Medical University, Chongqing 400016, China.
Jianwei WangChongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing Medical University, Chongqing 400016, China.

Funding

National Natural Science Foundation of China 82104469National Natural Science Foundation of China 82274164Natural Science Foundation of Chongqing cstc2021jcyj-bshX0161Scientific and Technological Research Program of Chongqing Municipal Education Commission KJQN202100417
6 · The paper itself

Abstract

Metabolic-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD), is a worldwide liver disease without definitive or widely used therapeutic drugs in clinical practice. In this study, we confirm that 6-gingerol (6-G), an active ingredient of ginger (

Indexed as

CatecholsFatty AlcoholsFructoseLipogenesisStearoyl-CoA DesaturaseAnimalsFatty LiverHep G2 CellsHumansLiverMaleMiceMice, Inbred C57BLMolecular Docking SimulationNon-alcoholic Fatty Liver DiseaseRatsCatecholsFatty AlcoholsFructosegingerolStearoyl-CoA DesaturaseTriglycerides6-gingerolhepatic steatosismetabolic-associated fatty liver diseasestearoyl-CoA desaturasetarget

Identifiers

PMID39457074
PMCPMC11508832

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.