Evidence map›Paper›PMID 39457597›Full record

ArticleBiomedicines2024

Association between Drug Use and Perception of Mental Health in Women Diagnosed with Fibromyalgia: An Observational Study.

Andrea Lizama-Lefno, Krystel Mojica, Ángel Roco-Videla, Juan Ignacio Vargas Ruiz-Tagle, Nelia González-Droguett, María Jesús Muñoz-Yánez, Erick Atenas-Núñez, Nelson Maureira-Carsalade, Sergio Flores Carrasco

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea Lizama-LefnoDirección de Desarrollo y Postgrados, Universidad Autónoma de Chile, Galvarino Gallardo 1983, Santiago 7500138, Chile.
Krystel MojicaFundación Núcleo de Investigación DOLMEN, El Director 6000, Of. 207, Las Condes, Santiago 7580023, Chile.ORCID 0009-0004-7730-0615
Ángel Roco-VidelaVicerrectoría de Investigación e Innovación, Universidad Arturo Prat, Iquique 1110939, Chile.ORCID 0000-0001-8850-1018
Juan Ignacio Vargas Ruiz-TagleClínica Andes Salud, Bellavista 123, Puerto Montt 5480000, Chile.ORCID 0000-0001-8533-8825
Nelia González-DroguettFundación Núcleo de Investigación DOLMEN, El Director 6000, Of. 207, Las Condes, Santiago 7580023, Chile.ORCID 0009-0001-4825-7839
María Jesús Muñoz-YánezUniversidad Gabriela Mistral, Av. Andrés Bello 1337, Santiago 7500533, Chile.ORCID 0000-0002-3902-5622
Erick Atenas-NúñezUniversidad Gabriela Mistral, Av. Andrés Bello 1337, Santiago 7500533, Chile.ORCID 0000-0001-7529-0514
Nelson Maureira-CarsaladeFacultad de Ingeniería, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.ORCID 0000-0003-2016-1154
Sergio Flores CarrascoInstituto de Geografía, Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesFibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and mental health issues. It affects approximately 1.78% of the general population; an estimated 4:1 ratio between women and men is observed. It significantly impacts quality of life and carries both clinical and social stigma. This study aims to evaluate the relationship between drug use and mental health in female patients with fibromyalgia.

methodsThis study is prospective, observational, and cross-sectional. A questionnaire was administered to 544 subjects, achieving a representative sample size from a population of 800,000 subjects by using an algorithm for proportion estimation with a known sampling frame. The selection was non-random, making the sampling non-probabilistic. Logistic regression models were applied to assess the effect of drug use on perception of mental health; presence of symptoms such as comprehension and memory problems, insomnia, depression, and anxiety; and severity of cognitive symptoms and non-restorative sleep. To quantify the impact, odds ratios and confidence intervals have been observed.

resultsThe findings indicate the non-recommended use of medications and reveal the ineffectiveness and adverse effects of drug interactions on mental health. The use of benzodiazepines and sedative-hypnotics is significantly associated with a negative perception of mental health. Benzodiazepines do not improve symptoms or significantly reduce their severity. SSRI antidepressants do not enhance mental health perception; however, when used exclusively, they are effective in reducing the severity, but not the prevalence, of cognitive symptoms.

conclusionsThe results highlight the complexity of pharmacological management in FM and raise concerns about the inappropriate use of ineffective or counterproductive drug interactions affecting patients' mental health. They underscore the need for multidisciplinary and personalized strategies that include close and careful monitoring, as well as the simultaneous use of non-pharmacological treatments that have demonstrated evidence in improving quality of life without negatively affecting mental health, such as patient education, psychological therapy, physiotherapy, and mindfulness.

Indexed as

benzodiazepinesdrug prescriptionsfibromyalgiamedication therapy managementmental healthpolypharmacyserotonin–norepinephrine reuptake inhibitors (SNRIs)sleep qualitywomen’s healthzolpidem

Identifiers

PMID39457597
PMCPMC11504724

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.