Evidence map›Paper›PMID 39457609›Full record

ArticleBiomedicines2024

Exploring the Relationship between Telomere Length and Cognitive Changes in Post-COVID-19 Subjects.

Guillermo Efrén Villar-Juárez, Alma Delia Genis-Mendoza, J Nicolas I Martínez-López, Ana Fresan, Carlos Alfonso Tovilla-Zaráte, German Alberto Nolasco-Rosales, Ghandy Isidro Juárez-De la Cruz, David Ruiz Ramos, Mario Villar-Soto, Paola Mejía-Ortiz and 3 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guillermo Efrén Villar-JuárezEscuela de Medicina, Universidad Anáhuac Querétaro, Querétaro 76246, Mexico.
Alma Delia Genis-MendozaInstituto Nacional de Medicina Genómica, Secretaría de Salud, Mexico City 14610, Mexico.
J Nicolas I Martínez-LópezInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.ORCID 0000-0002-0506-4076
Ana FresanInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.ORCID 0000-0001-9160-6988
Carlos Alfonso Tovilla-ZaráteDivisón Académica Multidisciplinaria de Comalcalco, Universidad Juarez Autónoma de Tabasco, Comalcalco 86658, Mexico.ORCID 0000-0001-8170-8171
German Alberto Nolasco-RosalesDivisión Académica de Ciencias de la Salud, Universidad Juarez Autónoma de Tabasco, Villahermosa 86100, Mexico.ORCID 0000-0001-5536-3173
Ghandy Isidro Juárez-De la CruzDivisión Académica de Ciencias de la Salud, Universidad Juarez Autónoma de Tabasco, Villahermosa 86100, Mexico.ORCID 0009-0004-7139-1691
David Ruiz RamosDivisión Académica de Ciencias de la Salud, Universidad Juarez Autónoma de Tabasco, Villahermosa 86100, Mexico.ORCID 0000-0003-1191-2577
Mario Villar-SotoHospital Regional de Alta Especialidad de Salud Mental, Villahermosa 86029, Mexico.
Paola Mejía-OrtizInstituto Nacional de Medicina Genómica, Secretaría de Salud, Mexico City 14610, Mexico.
Marlen Gómez MendiolaHospital Psiquiátrico Infantil Dr. Juan N. Navarro, Servicios de Atención Psiquiátrica, Mexico City 14080, Mexico.
Isela Esther Juárez-RojopDivisión Académica de Ciencias de la Salud, Universidad Juarez Autónoma de Tabasco, Villahermosa 86100, Mexico.
Humberto NicoliniInstituto Nacional de Medicina Genómica, Secretaría de Salud, Mexico City 14610, Mexico.ORCID 0000-0003-2494-0067

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesEmerging evidence suggests that patients suffering from COVID-19 may experience neurocognitive symptoms. Furthermore, other studies indicate a probable association between leukocyte telomere length (LTL) and neurocognitive changes in subjects with post-COVID-19 condition. Our study was designed to determine the correlation between telomere length and cognitive changes in post-COVID-19 subjects.

methodsThis study included 256 subjects, categorized based on SARS-CoV-2 infection from 2020 to 2023. In addition, subjects with a psychiatric diagnosis were considered. Moreover, the MoCA and MMSE scales were applied. Telomere length was determined using a polymerase chain reaction, and statistical analysis was employed using ANOVA and X

resultsWe identified a decrease in LTL in individuals with post-COVID-19 conditions compared to those without SARS-CoV-2 infection (

conclusionsThe findings suggest that LTL is affected by SARS-CoV-2 infection. Nonetheless, this important finding requires further research by monitoring neurological changes in subjects with post-COVID condition.

Indexed as

cognitive changespost-COVID-19SARS-CoV-2telomere length

Identifiers

PMID39457609
PMCPMC11504363

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.