Evidence map›Paper›PMID 39458265›Full record

ArticleMicroorganisms2024

Probio-Ichnos: A Database of Microorganisms with In Vitro Probiotic Properties.

Margaritis Tsifintaris, Despoina Eugenia Kiousi, Panagiotis Repanas, Christina S Kamarinou, Ioannis Kavakiotis, Alex Galanis

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Bile Salt Tolerance Determines Intestinal Colonization Efficacy ofInternational journal of molecular sciences · 2026
    Article
  8. Effects of Different Types ofFoods (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Probiotic Development Strategy Centered on Stability and Regulatory Considerations.Comprehensive reviews in food science and food safety · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margaritis TsifintarisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-8603-3767
Despoina Eugenia KiousiDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-4575-4776
Panagiotis RepanasDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Christina S KamarinouDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0009-0000-9565-3124
Ioannis KavakiotisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Alex GalanisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-9991-3173

Funding

EPAnEK MIS Code 5047285Hellenic Foundation for Research and Innovation Fellowship Number: 05704
6 · The paper itself

Abstract

Probiotics are live microorganisms that, when consumed in adequate amounts, exert health benefits on the host by regulating intestinal and extraintestinal homeostasis. Common probiotic microorganisms include lactic acid bacteria (LAB), yeasts, and Bacillus species. Here, we present Probio-ichnos, the first manually curated, literature-based database that collects and comprehensively presents information on the microbial strains exhibiting in vitro probiotic characteristics (i.e., resistance to acid and bile, attachment to host epithelia, as well as antimicrobial, immunomodulatory, antiproliferative, and antioxidant activity), derived from human, animal or plant microbiota, fermented dairy or non-dairy food products, and environmental sources. Employing a rigorous methodology, we conducted a systematic search of the PubMed database utilizing the keyword 'probiotic' within the abstracts or titles, resulting in a total of 27,715 studies. Upon further manual filtering, 2207 studies presenting in vitro experiments and elucidating strain-specific probiotic attributes were collected and used for data extraction. The Probio-ichnos database consists of 12,993 entries on the in vitro probiotic characteristics of 11,202 distinct strains belonging to 470 species and 143 genera. Data are presented using a binary categorization approach for the presence of probiotic attributes according to the authors' conclusions. Additionally, information about the availability of the whole-genome sequence (WGS) of strains is included in the database. Overall, the Probio-ichnos database aims to streamline the navigation of the available literature to facilitate targeted validation and comparative investigation of the probiotic properties of the microbial strains.

Indexed as

adhesionantimicrobial activityantioxidant capacityantiproliferationdatabaseimmunomodulationin vitro propertiesprobioticsstrain specificity

Identifiers

PMID39458265
PMCPMC11509836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.