Evidence map›Paper›PMID 39458422›Full record

ArticleNutrients2024

Comparison of Dietary Supplementation with Krill Oil, Fish Oil, and Astaxanthin on an Experimental Ethanol-Induced Gastric Ulcer Model: A Biochemical and Histological Study.

Esra Tansu Sarıyer, Murat Baş, Hatice Çolak, Naziye Özkan Yenal, Özlem Unay Demirel, Meral Yüksel

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esra Tansu SarıyerDepartment of Nutrition and Dietetics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0001-7042-9185
Murat BaşDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.ORCID 0000-0002-0494-301X
Hatice ÇolakDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Üsküdar University, 34662 Istanbul, Turkey.
Naziye Özkan YenalDepartment of Pathology Laboratory Techniques, Vocational School of Health-Related Services, Marmara University, 34865 Istanbul, Turkey.
Özlem Unay DemirelDepartment of Medical Biochemistry, Bahçeşehir University Göztepe Medical Park Hospital Central Laboratory, Faculty of Medicine, Bahçeşehir University, 34353 Istanbul, Turkey.
Meral YükselDepartment of Medical Laboratory Techniques, Vocational School of Health-Related Services, Marmara University, 34865 Istanbul, Turkey.ORCID 0000-0002-4760-3306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDespite advances in ulcer treatment research, the search for new, safe, and effective strategies for preventing and treating ulcer diseases persists.

methodsIn this study, the protective effects of dietary supplementation with krill oil (KO), fish oil (FO), and astaxanthin (ASX) on an ethanol-induced gastric ulcer model were compared during biochemical and histological observations. Sprague-Dawley (

resultsThe ulcer group showed increased levels of malondialdehyde (MDA), chemiluminescence (CL), and myeloperoxidase (MPO) activity and decreased levels of glutathione in the gastric tissues. While KO, FO, and ASX supplementation decreased chemiluminescence levels in the ulcer group, only ASX supplementation decreased MDA levels and MPO activity.

conclusionsIn conclusion, supplementation with KO or FO has a similar protective effect against ethanol-induced ulcer damage, as it inhibits ROS formation and reduces lipid peroxidation. However, ASX supplementation has a higher protective effect than KO or FO supplementations against experimental ethanol-induced gastric lesions in rats, as it inhibits ROS formation and reduces neutrophil infiltration and lipid peroxidation.

Indexed as

Dietary SupplementsDisease Models, AnimalEthanolEuphausiaceaFish OilsMalondialdehydeRats, Sprague-DawleyStomach UlcerXanthophyllsAnimalsGastric MucosaGlutathioneLipid PeroxidationMaleOxidative StressPeroxidaseastaxanthineEthanolFish OilsGlutathioneMalondialdehydePeroxidaseXanthophyllsantioxidantastaxanthinfish oilgastric ulcerkrill oilliveroxidative stress

Identifiers

PMID39458422
PMCPMC11510526

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.