Evidence map›Paper›PMID 39458484›Full record

ArticleNutrients2024

Continuous Glucose Monitor Metrics That Predict Neonatal Adiposity in Early and Later Pregnancy Are Higher in Obesity Despite Macronutrient-Controlled Eucaloric Diets.

Teri L Hernandez, Sarah S Farabi, Rachael E Van Pelt, Nicole Hirsch, Emily Z Dunn, Elizabeth A Haugen, Melanie S Reece, Jacob E Friedman, Linda A Barbour

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teri L HernandezCollege of Nursing, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
Sarah S FarabiDivision of Nutritional Science & Obesity Medicine, Department of Medicine, Washington University, St. Louis, MO 63130, USA.
Rachael E Van PeltDivision of Geriatric Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Nicole HirschCollege of Nursing, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
Emily Z DunnCollege of Nursing, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
Elizabeth A HaugenDivision of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Melanie S ReeceDivision of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Jacob E FriedmanHarold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.ORCID 0000-0002-6426-1512
Linda A BarbourDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · UNIVERSITY OF COLORADO DENVER · 1995 to 2025
$7.7M
Washington University Nutrition Obesity Research CenterP30DK056341 · WASHINGTON UNIVERSITY · 1999 to 2025
$5.7M
TRAINING PROGRAM IN DIABETES, ENDOCRINOLOGY &METABOLISMT32DK007446 · UNIVERSITY OF COLORADO DENVER · 1986 to 2005
$2.2M
National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases R01DK078645NCATS NIH HHS UL1 TR002535NIDDK NIH HHS P30 DK048520NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK078645NIDDK NIH HHS T32 DK007446NIH/NIDDK T32DK007446
6 · The paper itself

Abstract

backgroundFasting glucose is higher in pregnancies with obesity (OB); less is known about postprandial (PP) and nocturnal patterns when the diet is eucaloric and fixed or about the continuous-glucose-monitor (CGM) metrics that predict neonatal adiposity (NB%fat). We hypothesized that continuous glucose monitors (CGMs) would reveal higher glycemia in OB vs. normal weight (NW) during

methodsIn a prospective, parallel-group comparative study, a eucaloric diet (NW: 25 kcal/kg; OB: 30 kcal/kg) was provided (50% carbohydrate [20% simple/30% complex; of total calories], 35% fat, 15% protein) to Early and Later gestation groups wearing a blinded CGM for three days. CGM metrics (mean fasting; 1 h and 2 h PP; daytime and nocturnal glucose; percent time-in-range (%TIR: 63-140 mg/dL); PP excursions; and area-under-the-curve [AUC]) were interrogated between groups and as predictors of NB%fat by dual X-ray absorptiometry(DXA).

resultsFifty-four women with NW (BMI: 23 kg/m

conclusionsDespite macronutrient-controlled eucaloric diets, pregnancies with OB had higher glycemia Early and Later in gestation; the Later 24 h glucose AUC correlated with NB%fat. However, glycemic patterns were strikingly lower than current management targets.

Indexed as

AdiposityBlood GlucoseObesityPostprandial PeriodAdultBlood Glucose Self-MonitoringDietFemaleHumansInfant, NewbornNutrientsPregnancyPregnancy ComplicationsProspective StudiesBlood GlucoseNutrientsCGMdieteucaloricglucose metricsinfant adiposityobesitypregnancy

Identifiers

PMID39458484
PMCPMC11510187

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.