Evidence map›Paper›PMID 39458551›Full record

ArticleNutrients2024

Ouabain Ameliorates Alzheimer's Disease-Associated Neuropathology and Cognitive Impairment in FAD

Dan Wang, Jiajia Liu, Qizhi Zhu, Xin Wei, Xiang Zhang, Qi Chen, Yu Zhao, Heng Tang, Weiping Xu

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Mapping microglial mechanisms in Alzheimer's disease: a comprehensive analysis.Experimental biology and medicine (Maywood, N.J.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dan WangDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.ORCID 0009-0007-0384-1621
Jiajia LiuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Qizhi ZhuThe Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China.
Xin WeiThe Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China.
Xiang ZhangDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Qi ChenDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Yu ZhaoDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Heng TangDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Weiping XuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.

Funding

National Natural Science Foundation of China 52072360, 62305347
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDisease Models, AnimalMice, TransgenicOuabainAmyloid beta-PeptidesAnimalsHumansMaleMembrane GlycoproteinsMiceMicrogliaPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptors, ImmunologicSignal TransductionAmyloid beta-PeptidesMembrane GlycoproteinsOuabainPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptors, ImmunologicTrem2 protein, mouseAlzheimer’s diseasecognitive impairmentmicrogliaouabainTREM2

Identifiers

PMID39458551
PMCPMC11510559

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.