Evidence map›Paper›PMID 39458783›Full record

ArticlePlants (Basel, Switzerland)2024

Global Research Trends and Recent Advances in Medicinal Plant-Synthesized Nanoparticles for Cancer Treatment.

Tomi Lois Adetunji, Chijioke Olisah, Marvellous Amarachi Acho, Funsho Oyetunde-Joshua, Stephen O Amoo

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Neoplasia in the dromedary camel: a review (Frontiers in veterinary science · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tomi Lois AdetunjiAgricultural Research Council-Vegetables, Industrial and Medicinal Plants, Private Bag X293, Pretoria 0001, South Africa.
Chijioke OlisahInstitute for Coastal and Marine Research (CMR), Nelson Mandela University, P.O. Box 77000, Gqeberha 6031, South Africa.ORCID 0000-0002-7714-3056
Marvellous Amarachi AchoDepartment of Biochemistry, Landmark University, Omu-Aran 251103, Kwara State, Nigeria.ORCID 0000-0002-3772-311X
Funsho Oyetunde-JoshuaCenter of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.ORCID 0000-0001-5996-673X
Stephen O AmooAgricultural Research Council-Vegetables, Industrial and Medicinal Plants, Private Bag X293, Pretoria 0001, South Africa.ORCID 0000-0003-0009-5436

Funding

Department of Agriculture, Land Reform and Rural Development, South Africa N/A
6 · The paper itself

Abstract

Worldwide, cancer ranks among the foremost contributors to mortality despite recent medical progress. Alternative approaches in controlling various forms of cancer are being highly explored by researchers. This study provides the global research trends in the utilization of medicinal plant-synthesized nanoparticles for cancer treatment over the span of 18 years using scientometric analysis. Recent research advances on medicinal plant-derived nanoparticles for cancer treatment and their possible mechanisms of action were described. Relevant articles published between 2005 and 2023 were retrieved from Scopus and Web of Science and analyzed using RStudio and VOSViewer. Scientometric indicators were employed to analyze the results. The initial search returned 5695 articles, with a publication growth rate of 3.71% annually. Countries from Asia contributed the most (61.37%) to the total number of publications. The therapeutic effects of nanoparticles derived from medicinal plants can be attributed to various mechanistic pathways, including induced apoptosis from reactive oxygen species generation, as well as mitochondrial and cell membrane disruption, amongst others. Although some reported studies demonstrated promising safety and efficacy against certain cancer cells in vivo and in vitro, the little to no clinical data on medicinal plant-synthesized nanoparticles hinder the ability to make informed decisions about their clinical potential in cancer treatment.

Indexed as

anticancer activityapoptosisbibliometric analysisdrug deliverymedicinal plantsnanomedicine

Identifiers

PMID39458783
PMCPMC11511196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.