Evidence map›Paper›PMID 39459161›Full record

ArticleMolecules (Basel, Switzerland)2024

SARS-CoV-2 Nucleocapsid Protein Antagonizes GADD34-Mediated Innate Immune Pathway through Atypical Foci.

Jie Liu, Guanwen Guan, Chunxiu Wu, Bingbing Wang, Kaifei Chu, Xu Zhang, Su He, Naru Zhang, Geng Yang, Zhigang Jin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie LiuKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.
Guanwen GuanCollege of Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Chunxiu WuCollege of Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Bingbing WangCollege of Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Kaifei ChuKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.
Xu ZhangKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.
Su HeCollege of Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Naru ZhangKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.
Geng YangKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.
Zhigang JinCollege of Life Sciences, Zhejiang Normal University, Jinhua 321004, China.ORCID 0000-0001-7557-2968
Tiejun ZhaoKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China.

Funding

the National Natural Science Foundation of China 32370147; 31970755the Special Support Program for High-level Talents in Zhejiang Province 2023R5242
6 · The paper itself

Abstract

The integrated stress response, especially stress granules (SGs), contributes to host immunity. Typical G3BP1

Indexed as

Coronavirus Nucleocapsid ProteinsCOVID-19Immunity, InnateInterferon Regulatory Factor-3Protein Phosphatase 1RNA Recognition Motif ProteinsSARS-CoV-2AnimalsDNA HelicasesHEK293 CellsHumansPhosphoproteinsPoly-ADP-Ribose Binding ProteinsRNA HelicasesRNA, MessengerStress GranulesCoronavirus Nucleocapsid ProteinsDNA HelicasesG3BP1 protein, humanInterferon Regulatory Factor-3IRF3 protein, humannucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsPoly-ADP-Ribose Binding ProteinsPPP1R15A protein, humanProtein Phosphatase 1RNA HelicasesRNA, MessengerRNA Recognition Motif ProteinsGADD34innate immunitynucleocapsid proteinSARS-CoV-2stress granules

Identifiers

PMID39459161
PMCPMC11510332

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.