Evidence map›Paper›PMID 39459486›Full record

ReviewMedicina (Kaunas, Lithuania)2024

The Hidden Heart: Exploring Cardiac Damage Post-Stroke: A Narrative Review.

Marian Mitrică, Lorenzo Lorusso, Alexandru-Andrei Badea, Carmen-Adella Sîrbu, Andreea Pleșa, Ana-Maria Alexandra Stănescu, Florentina Cristina Pleșa, Octavian Mihai Sîrbu, Alice Elena Munteanu

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
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  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marian MitricăClinical Neurosciences Department, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Lorenzo LorussoNeurology Unit, Neuroscience Department A.S.S.T. Lecco, Merate Hospital, 23807 Merate, Italy.
Alexandru-Andrei BadeaDepartment of Cardiology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Carmen-Adella SîrbuClinical Neurosciences Department, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-1982-1066
Andreea PleșaDoctoral School, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Ana-Maria Alexandra StănescuDepartment No. 5, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-4807-9470
Florentina Cristina PleșaClinical Neurosciences Department, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Octavian Mihai SîrbuClinical Neurosciences Department, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alice Elena MunteanuDepartment of Cardiology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010825 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke-heart syndrome (SHS), a critical yet underrecognized condition, encompasses a range of cardiac complications that arise following an ischemic stroke. This narrative review explores the pathophysiology, clinical manifestations, and implications of SHS, focusing on the complex interplay between the brain and the heart. Acute ischemic stroke (AIS) triggers autonomic dysfunction, leading to a surge in catecholamines and subsequent myocardial injury. Our review highlights the five cardinal manifestations of SHS: elevated cardiac troponin (cTn) levels, acute myocardial infarction, left ventricular dysfunction, arrhythmias, and sudden cardiac death. Despite the significant impact of these complications on patient outcomes, there is a notable absence of specific guidelines for their management. Through a comprehensive literature search, we synthesized findings from recent studies to elucidate the mechanisms underlying SHS and identified gaps in the current understanding. Our findings underscore the importance of early detection and multidisciplinary management of cardiac complications post-stroke. Future research should focus on establishing evidence-based protocols to improve clinical outcomes for stroke patients with SHS. Addressing this unmet need will enhance the care of stroke survivors and reduce mortality rates associated with cardiac complications.

Indexed as

StrokeArrhythmias, CardiacDeath, Sudden, CardiacHumansIschemic StrokeMyocardial InfarctionTroponinVentricular Dysfunction, LeftTroponinautonomic dysfunctionbraincardiac dysfunctioncardiac enzymescatecholamine surgemyocardial dysfunctionneurogenic stress cardiomyopathyneurogenic stunned myocardiumstrokestroke–heart syndromeTakotsubo syndrome

Identifiers

PMID39459486
PMCPMC11509537

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.