Evidence map›Paper›PMID 39459583›Full record

ArticleLife (Basel, Switzerland)2024

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet.

Serpil Ciftel, Aleksandra Klisic, Enver Ciftel, Tolga Mercantepe, Adnan Yilmaz, Sedat Ciftel, Esra Pinarbas, Merve Nur Toraman, Filiz Mercantepe

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serpil CiftelDepartment of Endocrinology and Metabolism, Erzurum Training and Research Hospital, 25100 Erzurum, Turkey.
Aleksandra KlisicFaculty of Medicine, University of Montenegro, 81000 Podgorica, Montenegro.ORCID 0000-0001-7870-0996
Enver CiftelDepartment of Endocrinology and Metabolism, Sivas Numune Hospital, 58060 Sivas, Turkey.
Tolga MercantepeDepartment of Histology and Embryology, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey.ORCID 0000-0002-8506-1755
Adnan YilmazDepartment of Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey.ORCID 0000-0003-4842-1173
Sedat CiftelDepartment of Gastroenterology and Hepatology, Erzurum Training and Research Hospital, 25100 Erzurum, Turkey.ORCID 0000-0003-4905-1944
Esra PinarbasDepartment of Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey.
Merve Nur ToramanDepartment of Nutrition and Dietary, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey.
Filiz MercantepeDepartment of Endocrinology and Metabolism, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey.ORCID 0000-0002-4325-1534

Funding

Recep Tayyip Erdogan University Development Foundation 02024009030096
6 · The paper itself

Abstract

High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and white tea in rats fed a high-fat diet. Thirty-two rats were randomized into four groups: control (standard diet), HFD (high-fat diet), HFD+Orlistat (high-fat diet+orlistat), and HFD+WT (high-fat diet+white tea extract). A significant increase in malondialdehyde (MDA) levels and a decrease in total thiol (TT) levels were detected in the HFD group (

Indexed as

hepatosteatosishigh-fat dietliverNf-kB/p65ratwhite tea

Identifiers

PMID39459583
PMCPMC11509274

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.