Evidence map›Paper›PMID 39459616›Full record

ArticleLife (Basel, Switzerland)2024

The Nephroprotective Effect of

Sena Sahin Aktura, Kazim Sahin, Levent Tumkaya, Tolga Mercantepe, Atilla Topcu, Esra Pinarbas, Zihni Acar Yazici

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Antifungal Activity ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. IsLife (Basel, Switzerland) · 2025
    Article
  6. Vascular Endothelial Protection Effects ofInternational journal of medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sena Sahin AkturaDepartment of Medical Microbiology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.
Kazim SahinDepartment of Medical Microbiology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.ORCID 0000-0001-6126-8287
Levent TumkayaDepartment of Histology and Embryology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.
Tolga MercantepeDepartment of Histology and Embryology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.ORCID 0000-0002-8506-1755
Atilla TopcuDepartment of Pharmacology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.ORCID 0000-0003-4730-5015
Esra PinarbasDepartment of Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.
Zihni Acar YaziciDepartment of Medical Microbiology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.ORCID 0000-0003-1603-6545

Funding

Recep Tayyip Erdogan University Development Foundation 02024009018067
6 · The paper itself

Abstract

Sepsis is an exaggerated immune response resulting from systemic inflammation, which can damage tissues and organs. Acute kidney injury has been detected in at least one-third of patients with sepsis. Sepsis-associated acute kidney injury increases the risk of a secondary infection. Rapid diagnosis and appropriate initiation of antibiotics can significantly reduce mortality and morbidity. However, microorganisms are known to develop resistance to antibiotics. Estimations indicate that the annual casualties caused by microbial resistance will surpass cancer fatalities by 2050. The prevalence of bacterial infections and their growing antibiotic resistance has brought immediate attention to the search for novel treatments. Plant-derived supplements contain numerous bioactive components with therapeutic potential against a variety of conditions, including infections.

Indexed as

acute kidney injuryNF-κBPunica granatumsepsisTLR4

Identifiers

PMID39459616
PMCPMC11509784

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.