Evidence map›Paper›PMID 39459866›Full record

ReviewViruses2024

Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis.

Stephen Sinclair, Sean Shearen, Youssef Ghobrial, George Trad, Syed Abdul Basit, David Shih, John K Ryan

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen SinclairComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.
Sean ShearenComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.
Youssef GhobrialComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.
George TradComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.
Syed Abdul BasitComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.
David ShihComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.ORCID 0000-0003-1335-7044
John K RyanComprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B and Hepatitis C are viral causes of Hepatitis that lead to significant worldwide mortality and morbidity through the sequelae of fibrosis and hepatocellular carcinoma. In this review, we have summarized recent studies that have examined the effects of antiviral therapy on the regression of fibrosis and the reduction in mortalities associated with the viruses. Antiviral therapy significantly decreases mortality and induces the regression of fibrosis.

Indexed as

Antiviral AgentsHepatitis BLiver CirrhosisHepacivirusHepatitis B, ChronicHepatitis B virusHepatitis CHumansAntiviral Agentscirrhosisdecompensated cirrhosisfibrosisHBVHCVHepatitis BHepatitis Cliver-related mortalityportal hypertensionviral Hepatitis

Identifiers

PMID39459866
PMCPMC11512229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.