Evidence map›Paper›PMID 39459942›Full record

ArticleViruses2024

Double-Negative T-Cells during Acute Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections and Following Early Antiretroviral Therapy Initiation.

Alexis Yero, Tao Shi, Julien A Clain, Ouafa Zghidi-Abouzid, Gina Racine, Cecilia T Costiniuk, Jean-Pierre Routy, Jérôme Estaquier, Mohammad-Ali Jenabian

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Increased CD95Frontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexis YeroDepartment of Biological Sciences and CERMO-FC Research Centre, Université du Québec à Montréal (UQAM), Montreal, QC H2X 3X8, Canada.ORCID 0000-0002-7406-8740
Tao ShiDepartment of Biological Sciences and CERMO-FC Research Centre, Université du Québec à Montréal (UQAM), Montreal, QC H2X 3X8, Canada.
Julien A ClainCentre Hospitalier Universitaire (CHU) de Québec Centre de Recherche, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-7231-0847
Ouafa Zghidi-AbouzidCentre Hospitalier Universitaire (CHU) de Québec Centre de Recherche, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Gina RacineCentre Hospitalier Universitaire (CHU) de Québec Centre de Recherche, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Cecilia T CostiniukInfectious Diseases and Immunity in Global Health Program, Research Institute of McGill University Health Centre, Montreal, QC H3H 2R9, Canada.ORCID 0000-0002-4547-714X
Jean-Pierre RoutyInfectious Diseases and Immunity in Global Health Program, Research Institute of McGill University Health Centre, Montreal, QC H3H 2R9, Canada.ORCID 0000-0001-9897-7589
Jérôme EstaquierCentre Hospitalier Universitaire (CHU) de Québec Centre de Recherche, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-9432-8044
Mohammad-Ali JenabianDepartment of Biological Sciences and CERMO-FC Research Centre, Université du Québec à Montréal (UQAM), Montreal, QC H2X 3X8, Canada.ORCID 0000-0003-4321-9777

Funding

CIHR MOP 142294; HB2 164064; HBF-123682, HBF-126786, and MOP-133476Réseau SIDA et maladies infectieuses of the Fonds de recherche du Québec-Santé (FRQ-S) pilot studies
6 · The paper itself

Abstract

HIV infection significantly affects the frequencies and functions of immunoregulatory CD3

Indexed as

HIV InfectionsMacaca mulattaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsAnti-Retroviral AgentsFemaleHumansMaleT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsViral LoadAnti-Retroviral Agentsacute HIV infectionacute SIV infectionCD4−CD8− T-cellsdouble negative (DN) T-cellsearly ARTregulatory T-cells (Tregs)

Identifiers

PMID39459942
PMCPMC11512404

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.