Evidence map›Paper›PMID 39459949›Full record

ReviewViruses2024

Current State of Therapeutics for HTLV-1.

Tiana T Wang, Ashley Hirons, Marcel Doerflinger, Kevin V Morris, Scott Ledger, Damian F J Purcell, Anthony D Kelleher, Chantelle L Ahlenstiel

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. HTLV-1-associated diseases: a systematic review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Viral oncogenesis in cancer: from mechanisms to therapeutics.Signal transduction and targeted therapy · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiana T WangKirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-4292-272X
Ashley HironsThe Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3052, Australia.
Marcel DoerflingerWalter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
Kevin V MorrisCentre for Genomics and Personalised Health, School of Biomedical Sciences, Queensland University of Technology, Kelvin Grove, QLD 4059, Australia.ORCID 0000-0002-0157-0553
Scott LedgerKirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.
Damian F J PurcellThe Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3052, Australia.ORCID 0000-0002-4485-1726
Anthony D KelleherKirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.
Chantelle L AhlenstielKirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-4238-7237

Funding

Australian Centre for HIV and Hepatitis Virology Research (ACH4) Project GrantsAustralian NHMRC Ideas grant GNT2004670NHMRC program grant APP1149990NIH HHS R01 1R01MH134389-01 NIMH.
6 · The paper itself

Abstract

Human T cell leukaemia virus type-1 (HTLV-1) is an oncogenic retrovirus that causes lifelong infection in ~5-10 million individuals globally. It is endemic to certain First Nations populations of Northern and Central Australia, Japan, South and Central America, Africa, and the Caribbean region. HTLV-1 preferentially infects CD4

Indexed as

HTLV-I InfectionsHuman T-lymphotropic virus 1AnimalsAntiviral AgentsHumansLeukemia-Lymphoma, Adult T-CellViral VaccinesAntiviral AgentsViral Vaccinesantiviral therapeuticsATLHAMHTLV-1retrovirus

Identifiers

PMID39459949
PMCPMC11512412

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.