ArticleCommunications biology2024
Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- State-dependent signal flow hierarchy in the human cerebral cortex.Nature neuroscience · 2026Article
- Stronger right-hemispheric involvement in language processing is associated with greater functional connectivity between the left-lateralized language-related network and the cingulo-opercular network.Brain structure & function · 2026Article
- Human brain network for reading the mind from the eyes: beyond activated and deactivated regions.Social cognitive and affective neuroscience · 2026Article
- Acute effects of nitrous oxide on visual processing: a connectome study in healthy adults.Research square · 2026Article
- Task-dependent increases and decreases of BOLD signal in theory of mind brain regions during strategic social interaction.Frontiers in neural circuits · 2026Article
- Amyloid-beta relates to default and attention network connectivity during working memory retrieval.Brain communications · 2026Article
- Neural mechanisms of handedness for precision drawing: hand-dependent engagement of cortical networks for bimanual control and tool use.bioRxiv : the preprint server for biology · 2025Article
- Longitudinal functional connectivity during rest and task is differentially related to Alzheimer's pathology and episodic memory in older adults.Scientific reports · 2025Article
- Trauma Timing and Its Impact on Brain Activation During Flexible Emotion Regulation in PTSD: Insights From Functional MRI.Human brain mapping · 2025Article
- Twenty-Four Hour Rest-Activity Rhythm Disturbances and Neural Alterations Associated With Emotion Regulation in Shift Workers.Journal of sleep research · 2025Article
- Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The long-term correlates of developmental stress on whole-brain functional connectivity during emotion regulation.Translational psychiatry · 2025Article
- Common pitfalls during model specification in psychophysiological interaction analysis.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Task demands shape network interactions during reading and visual form processing.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Memory-related default-executive coupling across the lifespan and associations with changes in cognitive control.Imaging neuroscience (Cambridge, Mass.)Article
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5 authors.
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Abstract
Higher brain functions require flexible integration of information across widely distributed brain regions depending on the task context. Resting-state functional magnetic resonance imaging (fMRI) has provided substantial insight into large-scale intrinsic brain network organisation, yet the principles of rapid context-dependent reconfiguration of that intrinsic network organisation are much less understood. A major challenge for task connectome mapping is the absence of a gold standard for deriving whole-brain task-modulated functional connectivity matrices. Here, we perform biophysically realistic simulations to control the ground-truth task-modulated functional connectivity over a wide range of experimental settings. We reveal the best-performing methods for different types of task designs and their fundamental limitations. Importantly, we demonstrate that rapid (100 ms) modulations of oscillatory neuronal synchronisation can be recovered from sluggish haemodynamic fluctuations even at typically low fMRI temporal resolution (2 s). Finally, we provide practical recommendations on task design and statistical analysis to foster task connectome mapping.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.