Evidence map›Paper›PMID 39462384›Full record

ArticleLipids in health and disease2024

Plasma lipids and glycaemic indices in australians following plant-based diets versus a meat-eating diet.

Grace Austin, Jessica J A Ferguson, Shaun Eslick, Christopher Oldmeadow, Lisa G Wood, Manohar L Garg

Erratum issuedAbstract read
In one paragraph

Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Grace AustinSchool of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Jessica J A FergusonSchool of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Shaun EslickSchool of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Christopher OldmeadowClinical Research Design, Information Technology and Statistical Support Unit, Hunter Medical Research Institute, New Lambton, NSW, Australia.
Lisa G WoodSchool of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Manohar L GargSchool of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia. manohar.garg@mq.edu.au.

Funding

Bridging Scholarship and an Early Career small grant for statistical support from the Hunter Medical Research Institute 2101041Hunter Medical Research Institute Philanthropy funds 2200517Pilot grant from the College of Health, Medicine, and Well-being at the University of Newcastle 10-32804
6 · The paper itself

Abstract

backgroundVegan and vegetarian dietary patterns are known to beneficially modulate risk factors for cardiovascular disease; however, the current literature does not differentiate between various plant-based diets. This study aimed to examine the association between various plant-based diets and plasma lipids and glycaemic indices compared to a regular meat-eating diet.

methodsA cross-sectional study of Australian adults (n = 230) aged 30-75yrs habitually consuming the following were recruited: vegan, lacto-vegetarian, pesco-vegetarian, semi-vegetarian, or regular meat-eater. Multivariable regression analysis was used to adjust for covariates.

resultsCompared to regular meat-eaters, vegans had significantly lower total cholesterol (-0.77mmol/L,95% CI -1.15, -0.39, P < 0.001), low-density lipoprotein cholesterol (LDL-C, -0.71mmol/L, 95% CI -1.05, -0.38, P < 0.001), non-high-density lipoprotein cholesterol (non-HDL-C, -0.75mmol/L, 95% CI -1.11, -0.39, P < 0.001), total cholesterol/HDL-C-ratio (-0.49mmol/L, 95% CI -0.87, -0.11, P = 0.012), fasting blood glucose (FBG, -0.29mmol/L, 95% CI -0.53, -0.06, P = 0.014), haemoglobin A1C (-1.85mmol/mol, 95% CI -3.00, -0.71, P = 0.002) and insulin (-1.76mU/L, 95% CI -3.26, -0.26, P = 0.021) concentrations. Semi-vegetarians had significantly lower LDL-C (-0.41mmol/L, 95% CI -0.74, -0.08, P = 0.041) and non-HDL-C (-0.40mmol/L, 95% CI -0.76, -0.05, P = 0.026) and lacto-ovo vegetarians had significantly lower FBG (-0.34mmol/L, 95% CI -0.56, -0.11, P = 0.003) compared to regular meat-eaters. There were no differences in HDL-C and triglycerides between plant-based and regular-meat diets.

conclusionsPlasma lipaemic and glycaemic measures as a collective were more favourable among vegans, whereas among lacto-ovo vegetarians and semi-vegetarians, only some measures were favourable.

trial registrationACTRN12621000743864. Date 6/11/2021.

Indexed as

Diet, Plant-BasedGlycemic IndexMeatAdultAgedAustralasian PeopleAustraliaBlood GlucoseCholesterolCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDiet, VeganDiet, VegetarianFemaleGlycated HemoglobinBlood GlucoseCholesterolCholesterol, HDLCholesterol, LDLGlycated HemoglobinLipidsTriglyceridesCardio-vascular diseaseGlucoseInsulinLipidsPlant-basedT2D; dyslipidaemia; pesco-vegetarian; semi-vegetarianVeganVegetarian

Identifiers

PMID39462384
PMCPMC11514886

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.