Evidence map›Paper›PMID 39462596›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Hidden MODY in Young Lean Women with Mild Glucose Intolerance Detected during Health Check-ups: Potential for Improved Pregnancy Outcomes through Preconception Care.

Aya Osaki, Atsushi Ozawa, Akihito Morita, Daisuke Higeta, Shunpei Suda, Yoshiaki Ohtsu, Satoshi Yoshino, Syunichi Matsumoto, Kazuhiko Horiguchi, Eijiro Yamada

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aya OsakiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.
Atsushi OzawaDivision of Fundamental Nursing, Department of Nursing, Gunma University, Japan.
Akihito MoritaDepartment of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Japan.
Daisuke HigetaDepartment of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Japan.
Shunpei SudaDepartment of Pediatrics, Gunma University Graduate School of Medicine, Japan.
Yoshiaki OhtsuDepartment of Pediatrics, Gunma University Graduate School of Medicine, Japan.
Satoshi YoshinoDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.
Syunichi MatsumotoDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.
Kazuhiko HoriguchiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.
Eijiro YamadaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild glucose intolerance (positive urine glucose or mild hyperglycemia) during health checkups in young, lean women may require specialist consultation. We herein report a 31-year-old Japanese woman with mild hyperglycemia detected during a checkup who was diagnosed with overt diabetes in pregnancy and HNF4A-MODY postpartum, without prior follow-up. This case highlights the following: MODY may be present in young, lean women with mild glucose intolerance, and preconception care may improve pregnancy outcomes. Fetal outcomes vary with MODY subtype. Preconception care is important.

Indexed as

Diabetes Mellitus, Type 2Glucose IntolerancePreconception CareThinnessAdultFemaleHepatocyte Nuclear Factor 4HumansPregnancyPregnancy OutcomeHepatocyte Nuclear Factor 4medical checkupsMODYpreconception careyoung lean women

Identifiers

PMID39462596
PMCPMC12183403

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.