ArticlebioRxiv : the preprint server for biology2024
Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants.
Megna Tiwari, Elisabet Gas-Pascual, Manish Goyal, Marla Popov, Kenjiroo Matsumoto, Marianne Grafe, Ralph Graf, Robert S Haltiwanger, Neil Olszewski, Ron Orlando and 2 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
12 authors.
Elisabet Gas-PascualCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens GA.ORCID 0000-0002-2643-6916 Manish GoyalDepartment of Molecular and Cell Biology, Boston University School of Medicine, Boston MA.ORCID 0000-0003-2383-5409 Marla PopovGlycoScientific LLC, Athens, GA.
Kenjiroo MatsumotoComplex Carbohydrate Research Center, University of Georgia, Athens GA.
Marianne GrafeDept. of Cell Biology, Institute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.
Ralph GrafDept. of Cell Biology, Institute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.
Neil OlszewskiDepartment of Plant & Microbial Biology, University of Minnesota, 140 Gortner Laboratory, 1479 Gortner Avenue, St. Paul, MN 55108.ORCID 0000-0001-5393-7743 John SamuelsonDepartment of Molecular and Cell Biology, Boston University School of Medicine, Boston MA.ORCID 0000-0001-9533-3040 Christopher M WestCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens GA.ORCID 0000-0001-9077-965X Funding
Training in Tropical and Emerging Global Diseases - SupplementT32AI060546 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI Silvia N Moreno, Vasant Muralidharan · 2004 to 2026
$5.1MThe Biochemistry and Cell Biology of the SpindlyO-fucosyltransferase of ToxoplasmaR01GM129324 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SAMUELSON, JOHN C., WEST, CHRISTOPHER M. · 2020 to 2023
$2.1MO-glycosylation of cysteine-rich modulesR35GM148433 · NIGMS · UNIVERSITY OF GEORGIA · PI Robert S. Haltiwanger · 2023 to 2026
$1.8MNIAID NIH HHS T32 AI060546NIGMS NIH HHS R01 GM129324NIGMS NIH HHS R35 GM148433
6 · The paper itselfAbstract
Cellular adaptations to change often involve post-translational modifications of nuclear and cytoplasmic proteins. An example found in protists and plants is the modification of serine and threonine residues of dozens to hundreds of nucleocytoplasmic proteins with a single fucose (O-Fuc). A nucleocytoplasmic O-fucosyltransferase (OFT) occurs in the pathogen
Indexed as
Acanthamoeba castellaniiArabidopsis thalianaDictyostelium discoideumfucosyltransferasemono-glycosylationnuclear porenucleocytoplasmic glycosylationO-fucoseparasitesprotistssocial amoebaSpindlySPYToxoplasma gondii
Identifiers
PMID39464065
PMCPMC11507795
What Socratic holds
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