Evidence map›Paper›PMID 39464138›Full record

ArticlebioRxiv : the preprint server for biology2024

An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions.

Wenxue Li, Abhijit Dasgupta, Ka Yang, Shisheng Wang, Nisha Hemandhar-Kumar, Jay M Yarbro, Zhenyi Hu, Barbora Salovska, Eugenio F Fornasiero, Junmin Peng and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Wenxue LiDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Abhijit DasguptaDepartments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Ka YangDepartments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Shisheng WangDepartment of Pulmonary and Critical Care Medicine, and Proteomics-Metabolomics Analysis Platform, West China Hospital, Sichuan University, Chengdu 610041, China.
Nisha Hemandhar-KumarDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
Jay M YarbroDepartments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Zhenyi HuCancer Biology Institute, Yale University School of Medicine, West Haven, CT 06516, USA.
Barbora SalovskaDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Eugenio F FornasieroDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0001-7643-4962
Junmin PengDepartments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Yansheng LiuDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-2626-3912

Funding

Understanding how membrane composition directs membrane protein structure and functionRM1GM149406 · NIGMS · YALE UNIVERSITY · PI Joel Adam Butterwick, KATHRYN M FERGUSON · 2023 to 2026
$8.4M
Systems Approaches to Novel Molecular Mechanism in Alzheimer's DiseaseRF1AG064909 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI PENG, JUNMIN, YU, GANG · 2019 to 2024
$6.4M
Dissecting neuron-microglia-astrocyte interaction in AD pathogenesisRF1AG068581 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PENG, JUNMIN, ROSSOLL, WILFRIED · 2020 to 2023
$5.4M
Understanding proteome remodeling in aneuploidyR01GM137031 · NIGMS · YALE UNIVERSITY · PI LIU, YANSHENG · 2020 to 2024
$2.0M
NIA NIH HHS RF1 AG064909NIA NIH HHS RF1 AG068581NIGMS NIH HHS R01 GM137031NIGMS NIH HHS RM1 GM149406
6 · The paper itself

Abstract

Understanding how proteins in different mammalian tissues are regulated is central to biology. Protein abundance, turnover, and post-translational modifications like phosphorylation, are key factors that determine tissue-specific proteome properties. However, these properties are challenging to study across tissues and remain poorly understood. Here, we present

Identifiers

PMID39464138
PMCPMC11507808

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.