Evidence map›Paper›PMID 39464932›Full record

ArticleJournal of family medicine and primary care2024

Initiation or switch to insulin degludec/insulin aspart in adults with type 2 diabetes in India: Results from a prospective, non-interventional, real-world study.

Manash P Baruah, Pankaj Aneja, Shailesh Pitale, Abhijit Bhograj, Ritesh K Agrawala, Ajay Aggarwal, Prasad G Mahadev, Deepaklal C Madhavdas, Sanjay Shah, Mathew John and 4 more

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Manash P BaruahDepartment of Endocrinology, Apollo Excelcare Hospital, Guwahati, Assam, India.
Pankaj AnejaDepartment of Diabetes and Metabolic Diseases, Max Hospital, New Delhi, India.
Shailesh PitaleDepartment of Endocrinology, Dew Medicare and Trinity Hospital, Nagpur, Maharashtra, India.
Abhijit BhograjDepartment of Endocrinology, Columbia Asia Hospital, Bengaluru, Karnataka, India.
Ritesh K AgrawalaDepartment of Diabetology and Endocrinology, AMRI Hospital, Bhubaneswar, Odisha, India.
Ajay AggarwalDepartment of Endocrinology, Fortis Hospital, New Delhi, India.
Prasad G MahadevDepartment of Diabetology, Pranav Diabetes Center and Pace Clinical Research, Bengaluru, Karnataka, India.
Deepaklal C MadhavdasDepartment of Diabetology, RM Education Research Foundation, Chennai, Tamil Nadu, India.
Sanjay ShahDepartment of Diabetology and Endocrinology, Narayana Superspeciality Hospital, Kolkata, West Bengal, India.
Mathew JohnDepartment of Endocrinology, Providence Endocrine and Diabetes Specialty Centre, Thiruvananthapuram, Kerala, India.
Muzammil Khan A PathanDepartment of Clinical, Medical and Regulatory, Novo Nordisk India Private Limited, Bengaluru, Karnataka, India.
Manjunatha RevannaDepartment of Global Medical Affairs, Novo Nordisk A/S, Copenhagen, Denmark.
Manu ChandrappaDepartment of Clinical, Medical and Regulatory, Novo Nordisk India Private Limited, Bengaluru, Karnataka, India.
Kiran P SinghDepartment of Endocrinology, Fortis Hospital, Mohali, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate clinical outcomes in adults with type 2 diabetes (T2D) after insulin degludec/insulin aspart (IDegAsp) treatment in a real-world setting. Methods: The 26 weeks study involved 1102 adults with T2D who were either initiated with or switched to IDegAsp according to local practice in six countries. It was an open-label, non-interventional study. The primary endpoint was the change in glycosylated haemoglobin (HbA1c) levels from baseline to the end of study (EOS). Results: From India, 185 adults participated in this study with mean age of 58.1 (10.3) years and 14.4 (8.1) years of mean duration of T2D. Mean HbA1c decreased from 9.8% (1.8) at baseline to 8.2% (0.1) at the EOS; change in HbA1c from baseline [95% CI]: -1.6% (0.1) [-1.8; -1.4], Conclusion: Initiation or switching to IDegAsp led to improvement in glycaemic control in real-world population of Indian adults with T2D. This was accompanied by a numerical reduction in resource utilization and patient-reported hypoglycaemia.

Indexed as

IDegAspIndiaRWEtype 2 diabetes

Identifiers

PMID39464932
PMCPMC11504744

What Socratic holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.