Evidence map›Paper›PMID 39465641›Full record

SynthesisPublic health nutrition2024

Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis.

Abigail R Bournot, Andrea L Darling, Ian D Givens, Julie A Lovegrove, Susan A Lanham-New, Kathryn H Hart

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Public health nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abigail R BournotDepartment of Nutrition, Food & Exercise Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Andrea L DarlingDepartment of Nutrition, Food & Exercise Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.ORCID 0000-0002-7038-3161
Ian D GivensInstitute for Food, Nutrition and Health, University of Reading, Reading, UK.
Julie A LovegroveInstitute for Food, Nutrition and Health, University of Reading, Reading, UK.
Susan A Lanham-NewDepartment of Nutrition, Food & Exercise Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Kathryn H HartDepartment of Nutrition, Food & Exercise Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis systematic review and meta-analysis examined the evidence for a potential relationship between vitamin D status and vitamin D supplementation on immune function biomarkers and prevention of acute respiratory tract infections (ARTI) in dark-skinned individuals.

designSix databases were searched (inception to December 2021) for randomised controlled trials (RCT) and observational studies. A narrative synthesis and random-effects meta-analysis were used to synthesise the findings.

settingNot applicable.

participantsEthnic groups other than white, with or without a white comparator.

resultsAfter duplicates were removed, 2077 articles were identified for screening. A total of eighteen studies (

conclusionsThere is a lack of conclusive evidence supporting an association between vitamin D status and immune function or ARTI incidence in dark-skinned individuals. Further RCT in diverse ethnic populations are urgently needed.

Indexed as

Dietary SupplementsRespiratory Tract InfectionsVitamin DAcute DiseaseBiomarkersEthnicityHumansRandomized Controlled Trials as TopicSkin PigmentationVitamin D DeficiencyBiomarkersVitamin D25(OH)DEthnic groupImmune functionRace/ethnicityRespiratory tract infectionVitamin D

Identifiers

PMID39465641
PMCPMC11645122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.