Evidence map›Paper›PMID 39466381›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Influence of implant density on mechanical complications in adult spinal deformity surgery.

Yann Philippe Charles, François Severac, Susana Núñez-Pereira, Sleiman Haddad, Lluis Vila, Ferran Pellisé, Ibrahim Obeid, Louis Boissière, Caglar Yilgor, Altug Yucekul and 8 more

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Stabilization of L5 pedicle Subtraction osteotomies (PSO) with ≥ 6-rods and bilateral dual pelvic fixation with osseointegrative implants: surgical technique description and early postoperative outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Yann Philippe CharlesDepartment of Spine Surgery, Strasbourg University Hospital, 1 Avenue Molière, 67200, Strasbourg, France. YannPhilippe.CHARLES@chru-strasbourg.fr.ORCID 0000-0002-0606-211X
François SeveracDepartment of Public Health, Strasbourg University Hospital, Strasbourg, France.
Susana Núñez-PereiraSpine Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.
Sleiman HaddadSpine Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.
Lluis VilaSpine Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.
Ferran PelliséSpine Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.
Ibrahim ObeidSpine Surgery Unit 1, Bordeaux University Hospital, Bordeaux, France.
Louis BoissièreSpine Surgery Unit 1, Bordeaux University Hospital, Bordeaux, France.
Caglar YilgorDepartment of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.
Altug YucekulDepartment of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.
Ahmet AlanayDepartment of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.
Frank KleinstückSchulthess Klinik, Zurich, Switzerland.
Markus LoiblSchulthess Klinik, Zurich, Switzerland.
Alejandro Gómez-RiceSpine Unit, Department of Orthopaedic Surgery, Hospital Universitario de Getafe, Madrid, Spain.
Riccardo RaganatoSpine Surgery Unit, Hospital Universitario La Paz, Madrid, Spain.
Francisco Javier Sánchez Perez-GruesoSpine Surgery Unit, Hospital Universitario La Paz, Madrid, Spain.
Javier PizonesSpine Surgery Unit, Hospital Universitario La Paz, Madrid, Spain.
European Spine Study Group (ESSG)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose was to analyze how rod characteristics, screw density and cages influence the incidence of mechanical complications compared to patient-related factors and alignment in adult spinal deformity instrumented T9-T11 to pelvis.

methodsRegister data of 302 patients was analyzed. Relative lumbar lordosis (RLL) and relative sagittal alignment (RSA) was measured. Surgical data included rod characteristics, pedicle screw density and interbody cages. Univariate and multivariate logistic regression models were used.

resultsPseudarthrosis occurred in 24.1%. On univariate analysis Odds Ratio (OR) was 0.74 for ≥ 3 cages (p = 0.452), 0.48 for 4 rods (p = 0.008), 4.30 for high screw density (p = 0.001). Patient-related factors were non-significant. Multivariate OR was 0.59 for 4 rods (p = 0.084) and 4.67 for high screw density (p = 0.005). PJK/PJF occurred in 19.2%. Age > 60 had an OR 2.83 (p = 0.023), postoperative RSA malaligned OR 2.84 (p = 0.030), severely malaligned OR 6.54 (p < 0.001). Implant characteristics were non-significant. Multivariate OR was 1.26 for age > 60 (p = 0.657), 2.32 for malaligned RSA (p = 0.097), 5.69 for severely malaligned RSA (p = 0.001). Screw loosening occurred in 8.9%. Univariate OR was 0.95 for ≥ 3 cages (p = 0.920), 1.64 for 4 rods (p = 0.235), 0.25 for high screw density 1.5-2 (p = 0.011). Patient-related factors were non-significant. Multivariate OR for high screw density was 0.23 (p = 0.022).

conclusionFour rods decrease the pseudarthrosis risk. Cages have a secondary role. High screw density doesn't prevent from pseudarthrosis. Postoperative malalignment is the main PJK/PJF risk factor. Age plays a secondary role. Implant characteristics have a minor influence. High screw density constructs have a lower risk for screw loosening. LEVEL OF EVIDENCE: 3-Retrospective register study.

Indexed as

Postoperative ComplicationsSpinal FusionAdultAgedAged, 80 and overFemaleHumansLordosisMaleMiddle AgedPedicle ScrewsPseudarthrosisRetrospective StudiesSpinal CurvaturesAdult spinal deformityAgeImplant densityMechanical complicationSagittal alignment

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.