Evidence map›Paper›PMID 39467097›Full record

ArticleJournal of magnetic resonance imaging : JMRI2025

Improving Accuracy and Reproducibility of Cartilage T

Marco Barbieri, Anthony A Gatti, Feliks Kogan

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marco BarbieriDepartment of Radiology, Stanford University, Stanford, California, USA.ORCID 0000-0002-8795-1073
Anthony A GattiDepartment of Radiology, Stanford University, Stanford, California, USA.
Feliks KoganDepartment of Radiology, Stanford University, Stanford, California, USA.

Funding

Imaging of Joint Response to Physiological Stress with Age, Sex and in OsteoarthritisR01AR079431 · NIAMS · STANFORD UNIVERSITY · PI Feliks Kogan · 2022 to 2026
$2.9M
Novel Non-Contrast MRI to Assess Synovitis in OsteoarthritisR01AR083018 · NIAMS · STANFORD UNIVERSITY · PI Feliks Kogan · 2024 to 2026
$1.6M
Quantitative Assessment of Early Metabolic and Biochemical Changes in OsteoarthritisR00EB022634 · NIBIB · STANFORD UNIVERSITY · PI KOGAN, FELIKS · 2019 to 2021
$730k
NIAMS NIH HHS R01 AR079431NIAMS NIH HHS R01 AR083018NIBIB NIH HHS R00 EB022634
6 · The paper itself

Abstract

backgroundThe Osteoarthritis Initiative (OAI) collected extensive imaging data, including Multi-Echo Spin-Echo (MESE) sequences for measuring knee cartilage T PURPOSE: To assess how different fitting methods, including EPG-based and exponential-based approaches, affect the accuracy and reproducibility of cartilage T STUDY TYPE: Retrospective. POPULATION: From OAI dataset, 50 subjects, stratified by osteoarthritis (OA) severity using Kellgren-Lawrence grades (KLG), and 50 subjects without OA diagnosis during OAI duration were selected (each group: 25 females, mean ages ~61 years). FIELD STRENGTH/SEQUENCE: 3-T, two-dimensional (2D) MESE sequence. ASSESSMENT: Femoral and tibial cartilages were segmented from DESS images, subdivided into seven sub-regions, and co-registered to MESE. T STATISTICAL TESTS: Bland-Altman analysis, Lin's concordance coefficient, and coefficient of variation assessed agreement, repeatability, and reproducibility. Statistical significance was set at P-value <0.05.

resultsEPG-based methods demonstrated superior T DATA

conclusionEPG modeling improved agreement and reproducibility of cartilage T EVIDENCE LEVEL: 3 TECHNICAL EFFICACY: Stage 1.

Indexed as

Cartilage, ArticularMagnetic Resonance ImagingOsteoarthritis, KneeAgedAlgorithmsFemaleHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedKnee JointMaleMiddle AgedReproducibility of ResultsRetrospective Studiesknee imagingMESEosteoarthritisOsteoarthritis InitiativeT2 mapping

Identifiers

PMID39467097
PMCPMC13045094

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.