Evidence map›Paper›PMID 39467547›Full record

ArticleACS applied materials & interfaces2024

Bioprinting PDLSC-Laden Collagen Scaffolds for Periodontal Ligament Regeneration.

Isaac J de Souza Araújo, Rachel S Perkins, Mohamed Moustafa Ibrahim, George T-J Huang, Wenjing Zhang

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. Biofabrication - Revolutionizing the future of regenerative periodontics.Dental materials : official publication of the Academy of Dental Materials · 2025
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isaac J de Souza AraújoDepartment of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States.ORCID 0000-0002-1795-8640
Rachel S PerkinsDepartment of Orthopaedic Surgery and Biomedical Engineering, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States.ORCID 0000-0001-8780-3305
Mohamed Moustafa IbrahimDepartment of Ophthalmology, Hamilton Eye Institute, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States.ORCID 0000-0001-7691-6128
George T-J HuangDepartment of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States.
Wenjing ZhangDepartment of Genetics, Genomics & Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States.ORCID 0000-0002-6694-6072

Funding

Personalized bioprinting technology for de novo PDL regenerationR21DE032151 · NIDCR · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HUANG, GEORGE T.J, ZHANG, WENJING · 2023 to 2023
$424k
NIDCR NIH HHS R21 DE032151
6 · The paper itself

Abstract

Periodontitis and severe trauma are major causes of damage to the periodontal ligament (PDL). Repairing the native conditions of the PDL is essential for the stability of the tissue and its interfaces. Bioprinting periodontal ligament stem cells (PDLSCs) is an interesting approach to guide the regeneration of PDL and interfacial integration. Herein, a collagen-based bioink mimicking the native extracellular matrix conditions and carrying PDLSCs was tested to guide the periodontal ligament organization. The bioink was tested at two different concentrations (10 and 15 mg/mL) and characterized by swelling and degradation, microstructural organization, and rheological properties. The biological properties were assessed after loading PDLSCs into bioinks for bioprinting. The characterization was performed through cell viability, alizarin red assay, and expression for

Indexed as

BioprintingCollagenPeriodontal LigamentRegenerationStem CellsTissue ScaffoldsAnimalsCell DifferentiationCell ProliferationCell SurvivalHumansMiceCollagenBioprintingCollagenPeriodontal ligamentRegenerationStem Cells

Identifiers

PMID39467547
PMCPMC11551894

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.