Evidence map›Paper›PMID 39468133›Full record

Trial reportScientific reports2024

Gastrointestinal and respiratory morbidity when introducing eggs as complementary food: a randomised controlled trial in South African infants.

Regina Nakiranda, Linda Malan, Hannah Ricci, Herculina S Kruger, Arista Nienaber, Marina Visser, Cristian Ricci, Mieke Faber, Cornelius M Smuts

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Daily egg intake may reduce sensitisation to common allergenic foods among six- to nine-month-old south African infants: A randomized controlled trial.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Regina NakirandaNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa. reginaki30@gmail.com.ORCID http://orcid.org/0000-0001-8057-2751
Linda MalanNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Hannah RicciNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Herculina S KrugerNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Arista NienaberNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Marina VisserNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Cristian RicciAfrica Unit for Transdisciplinary Health Research (AUTHeR), North-West University, Potchefstroom, South Africa.
Mieke FaberNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.
Cornelius M SmutsNorth-West University (Centre of Excellence for Nutrition), Potchefstroom, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the incidence and duration of morbidity symptoms among infants aged 6 to 9 months from a low socioeconomic community receiving one egg daily for 6 months. This was a secondary outcome of a randomised controlled trial (RCT) of 500 infants conducted in Jouberton, South Africa. The primary outcome was linear growth. Morbidity data were collected weekly using a symptoms diary and qualitative data with focus group discussions at the endpoint. Ethical approval was obtained from the North-West University Health Research Ethics Committee. The intervention group had a ~ 5% higher incidence of gastrointestinal morbidity (17.0%) compared to the control group (11.9%). Gastrointestinal morbidity without fever tended to be 1.4 times higher in the intervention group (OR: 1.43, 95% CI: 1.03, 1.93; P = 0.058) and tended to be 4 times higher with fever (OR: 4.07, 95% CI: 0.86, 19.23; P = 0.077). The duration of total gastrointestinal and respiratory morbidity was 1.5 days longer in the intervention group (β: 1.491; 95% CI 0.064, 2.918; P = 0.041). Complementary feeding with eggs may have contributed towards an increased risk for gastrointestinal morbidity.

Indexed as

EggsGastrointestinal DiseasesInfant Nutritional Physiological PhenomenaFemaleHumansIncidenceInfantMaleMorbidityRespiratory Tract DiseasesSouth Africa

Identifiers

PMID39468133
PMCPMC11519461

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.