Evidence map›Paper›PMID 39468417›Full record

Trial reportClinical obesity2025

Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial.

Michelle A J van Oeteren, Nynke Simons, Pomme I H G Simons, Marjo P H van de Waarenburg, M Eline Kooi, Edith J M Feskens, E M C Liesbeth van der Ploeg, Mathias D G Van den Eynde, Alfons J H M Houben, Casper G Schalkwijk and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical obesity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michelle A J van OeterenLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.ORCID https://orcid.org/0009-0000-2572-5305
Nynke SimonsLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Pomme I H G SimonsLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Marjo P H van de WaarenburgLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
M Eline KooiCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Edith J M FeskensDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
E M C Liesbeth van der PloegDepartment of Dietetics, Maastricht University Medical Center, Maastricht, The Netherlands.
Mathias D G Van den EyndeLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Alfons J H M HoubenLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Casper G SchalkwijkLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Martijn C G J BrouwersLaboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

Funding

Netherlands Heart Foundation 2015T042 (to MCGJB)Nutricia Research Foundation 2016-33 (to MCGJB)
6 · The paper itself

Abstract

We aimed to examine the effects of isocaloric fructose restriction on adipose tissue distribution and serum adipokines. Individuals with BMI >28 kg/m

Indexed as

AdipokinesFructoseAdiponectinAdipose TissueAdultBody Mass IndexDouble-Blind MethodFemaleHumansIntra-Abdominal FatMaleMiddle AgedSubcutaneous FatAdipokinesAdiponectinFructoseadipokinesadipose tissue distributionBMIdietary interventionfructose

Identifiers

PMID39468417
PMCPMC11706758

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.