Evidence map›Paper›PMID 39472027›Full record

ArticleMolecular pharmacology2024

Receptor Determinants for β-Arrestin Functional Specificity at

Joseph M Crecelius, Aaren R Manz, Sara Benzow, Adriano Marchese

Abstract read
In one paragraph

Article in Molecular pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. GPCR Biased Signaling in Cancer.Handbook of experimental pharmacology · 2026
    Review
  2. CXCL13/CXCR5: a new target for pain treatment.International journal of surgery (London, England) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph M CreceliusDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin.
Aaren R ManzDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin.
Sara BenzowDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin.
Adriano MarcheseDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin amarchese@mcw.edu.

Funding

Role of beta-arrestins in G protein-coupled receptor sorting and signalingR01GM106727 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2014 to 2022
$2.9M
Regulation of chemokine receptor signalingR35GM149253 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI Adriano Marchese · 2023 to 2026
$1.8M
Bi-directional regulation of chemokine receptor signalingR01GM143808 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2021 to 2023
$1.1M
NIGMS NIH HHS R01 GM106727NIGMS NIH HHS R01 GM143808NIGMS NIH HHS R35 GM149253
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-ArrestinsReceptors, CXCR5Arrestinsbeta-Arrestin 1beta-Arrestin 2HEK293 CellsHumansPhosphorylationSignal TransductionArrestinsbeta-Arrestin 1beta-Arrestin 2beta-ArrestinsCXCR5 protein, humanReceptors, CXCR5

Identifiers

PMID39472027
PMCPMC11585254

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.