Evidence map›Paper›PMID 39473074›Full record

SynthesisDiabetic medicine : a journal of the British Diabetic Association2025

The effect of high-fibre diets on glycaemic control in women with diabetes in pregnancy: A systematic review and meta-analysis.

Danielle Jones, Anna Kyriakidou, Louise Cooper, Nooria Atta, Patrycja Tobolska, Suzanne Smith, Elizabeth Turner, Clive Petry, Clare Gillies, Claire L Meek

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Diabetic medicine : a journal of the British Diabetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danielle JonesInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0003-0372-5579
Anna KyriakidouBarnet Hospital, Royal Free London NHS Foundation Trust, Wellhouse Lane, London, UK.
Louise CooperMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Nooria AttaInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
Patrycja TobolskaInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
Suzanne SmithInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
Elizabeth TurnerInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
Clive PetryInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
Clare GilliesLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
Claire L MeekInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-4176-8329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary fibre improves glycaemic control in type 2 diabetes, but its therapeutic role in women with diabetes in pregnancy is unclear. We assessed the effect of dietary fibre on markers of glycaemic control in women with diabetes in pregnancy.

methodsWe searched four databases (Cochrane Library, MEDLINE, Embase and Web of Science) to identify RCTs exploring the effect of dietary fibre, high-fibre diets or fibre supplementation on fasting blood glucose (FBG), 2-h postprandial blood glucose (PBG) and requirement for insulin therapy, among other glycaemic makers in pregnant women with diabetes. Data were pooled for each outcome to calculate change from baseline mean (SD) and overall mean difference (MD) between control and intervention groups.

resultsOf 1462 identified studies, data from 20 eligible trials containing 1061 participants were pooled. On meta-analysis, a higher fibre intake was associated with reduced FBG (MD: -0.35 mmol/L, 95% CI: -0.53, -0.18, p < 0.01), PBG (MD: -0.90 mmol/L, 95% CI: -1.39, -0.40, p < 0.01) and requirement for insulin (OR: 0.24, 95% CI: 0.13, 0.46, p < 0.01). There was significant heterogeneity for FBG and PBG (>90%), attributable to differences in Intervention type for PBG (Dietary Approach to Stop Hypertension [DASH] diet, low glycaemic index, supplement; p < 0.01) and study duration (for FBG: p = 0.002; not for PBG). Studies were mostly scored as high risk of bias due to lack of blinding (Cochrane Risk of Bias Tool v.2.0).

conclusionHigh-quality dietary intervention studies in pregnancy are lacking. Our results suggest that high-fibre diets improve fasting and postprandial glycaemia and reduce the likelihood of requiring insulin in women with diabetes in pregnancy.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2Dietary FiberGlycemic ControlPregnancy in DiabeticsFemaleHumansInsulinPregnancyBlood GlucoseDietary FiberInsulindiabetes in pregnancydietary fibreglucose controlinsulin requirements

Identifiers

PMID39473074
PMCPMC11635591

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.