Evidence map›Paper›PMID 39475274›Full record

ArticleJournal of virology2024

Stimulation of neutral lipid synthesis via viral growth factor signaling and ATP citrate lyase during vaccinia virus infection.

Anil Pant, Djamal Brahim Belhaouari, Lara Dsouza, Zhilong Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Integrative Adipogenic Engineering of Cultured Fat for Cell Based Meat.Comprehensive reviews in food science and food safety · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anil PantDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-4914-1771
Djamal Brahim BelhaouariDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-1112-9921
Lara DsouzaDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Zhilong YangDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-8995-2654

Funding

Mechanisms regulating poxvirus post-replicative protein synthesisR01AI143709 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI YANG, ZHILONG · 2019 to 2023
$1.9M
HHS | National Institutes of Health (NIH) R01AI143709NIAID NIH HHS R01 AI143709
6 · The paper itself

Abstract

Fatty acid metabolism can provide various products essential for viral infections. How vaccinia virus (VACV), the prototype of poxviruses, modulates fatty acid metabolism is not well understood. Here, we show that VACV infection results in increased neutral lipid droplet synthesis, the organelles that play a crucial role in storing and mobilizing fatty acids for energy production via β-oxidation. Citrate is the first tricarboxylic acid (TCA) cycle intermediate that can be transported to the cytosol to be converted to acetyl-CoA for

Indexed as

ATP Citrate (pro-S)-LyaseLipid MetabolismSignal TransductionVaccinia virusVirus ReplicationErbB ReceptorsFatty AcidsHumansIntercellular Signaling Peptides and ProteinsLipid DropletsPhosphorylationProto-Oncogene Proteins c-aktVacciniaATP Citrate (pro-S)-LyaseEGFR protein, humanErbB ReceptorsFatty AcidsIntercellular Signaling Peptides and ProteinsProto-Oncogene Proteins c-aktATP citrate lyaseEGFRfatty acidslipid dropletsmetabolismpoxvirusvaccinia virus

Identifiers

PMID39475274
PMCPMC11578090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.