Evidence map›Paper›PMID 39475281›Full record

ArticlemBio2024

Epidermal growth factor receptor signaling governs the host inflammatory response to invasive aspergillosis.

Hong Liu, Jianfeng Lin, Quynh T Phan, Vincent M Bruno, Scott G Filler

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. mBio · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Hong LiuDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0009-0008-3804-9535
Jianfeng LinDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0002-5202-6304
Quynh T PhanDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Vincent M BrunoDepartment of Microbiology and Immunology, University of Maryland, Baltimore, Maryland, USA.ORCID 0000-0003-1683-2015
Scott G FillerDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0001-7278-3700

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FRASER, CLAIRE M., RASKO, DAVID A · 2014 to 2023
$36.5M
Transcriptional networks governing A. fumigatus virulenceR01AI162802 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MOYE-ROWLEY, W SCOTT · 2021 to 2025
$3.3M
Transcriptional regulation of A. fumigatus virulenceR01AI073829 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G · 2007 to 2015
$2.8M
Therapeutic targeting of growth factor receptors to treat MucormycosisR01AI141360 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BRUNO, VINCENT MICHAEL · 2019 to 2023
$2.5M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI141360HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI162802HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI110820NIAID NIH HHS R01 AI073829NIAID NIH HHS R01 AI141360NIAID NIH HHS R01 AI162802NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

The epidermal growth factor receptor (EGFR) has been identified as an epithelial cell receptor for Mucorales fungi and

Indexed as

Aspergillus fumigatusEpithelial CellsErbB ReceptorsSignal TransductionAnimalsCell LineCytokinesDisease Models, AnimalFemaleGefitinibHost-Pathogen InteractionsHumansInflammationInvasive Pulmonary AspergillosisLungMiceCytokinesEGFR protein, mouseErbB ReceptorsGefitinibalveolar epithelial cellAspergillus fumigatuschemokinecytokineendocytosisepidermal growth factor receptorsmall-airway epithelial cell

Identifiers

PMID39475281
PMCPMC11633379

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.