Evidence map›Paper›PMID 39476178›Full record

ArticleJournal of gastroenterology2025

Conditional deletion of IP

Hong Wang, Beili Zhao, Lei Huang, Xiangbin Zhu, Na Li, Can Huang, Zhen Han, Kunfu Ouyang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hong Wang *Central Laboratory, Peking University Shenzhen Hospital, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Peking University, Shenzhen, 518036, China.
Beili Zhao *Central Laboratory, Peking University Shenzhen Hospital, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Peking University, Shenzhen, 518036, China.
Lei Huang *Department of Cardiovascular Surgery, Peking University Shenzhen Hospital, Peking University, Shenzhen, 518036, China.
Xiangbin ZhuDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Peking University, Shenzhen, 518036, China.
Na LiDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Peking University, Shenzhen, 518036, China.
Can HuangDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Peking University, Shenzhen, 518036, China.
Zhen HanDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Peking University, Shenzhen, 518036, China. 2547671020@qq.com.
Kunfu OuyangCentral Laboratory, Peking University Shenzhen Hospital, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Peking University, Shenzhen, 518036, China. ouyang_kunfu@pku.edu.cn.ORCID 0000-0003-0292-375X

Funding

National Natural Science Foundation of China 81970421National Natural Science Foundation of China 82170235
6 · The paper itself

Abstract

BACKGROUND AND

aimsInositol 1,4,5-trisphosphate receptor type 1 (IP

methodsConditional IP

resultsIn the mouse GI tract, Islet1-Cre targeted smooth muscle cells (SMCs) and interstitial cells of Cajal (ICCs), but not enteric neurons. IP

conclusionsIP

Indexed as

Gastrointestinal MotilityInositol 1,4,5-Trisphosphate ReceptorsInterstitial Cells of CajalAnimalsGastrointestinal TransitGene DeletionIntegrasesIntestinal Pseudo-ObstructionLIM-Homeodomain ProteinsMiceMice, KnockoutMyocytes, Smooth MuscleTranscription FactorsInositol 1,4,5-Trisphosphate Receptorsinsulin gene enhancer binding protein Isl-1IntegrasesItpr1 protein, mouseLIM-Homeodomain ProteinsTranscription FactorsGastrointestinal motilityInterstitial cells of CajalIntestinal pseudo-obstructionIP3 receptorSmooth muscle contraction

Identifiers

PMID39476178

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.