Evidence map›Paper›PMID 39477423›Full record

ArticleIn vivo (Athens, Greece)

Elevated Circulatory Levels of UL16 Binding Protein 1 Positive Microparticles Are Associated With Acute Myocardial Infarction and its Severity.

Songpol Haohan, Burabha Pussadhamma, Amonrat Jumnainsong, Wit Leuangwatthananon, Pattarapong Makarawate, Chanvit Leelayuwat, Nantarat Komanasin

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PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Songpol HaohanCardiovascular Research Group, Khon Kaen University, Khon Kaen, Thailand.
Burabha PussadhammaCardiovascular Research Group, Khon Kaen University, Khon Kaen, Thailand.
Amonrat JumnainsongSchool of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Wit LeuangwatthananonQueen Sirikit Heart Center of the Northeast Hospital, Khon Kaen University, Khon Kaen, Thailand.
Pattarapong MakarawateCardiovascular Research Group, Khon Kaen University, Khon Kaen, Thailand.
Chanvit LeelayuwatSchool of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Nantarat KomanasinCardiovascular Research Group, Khon Kaen University, Khon Kaen, Thailand; nankom@kku.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAtherosclerosis is a vascular inflammatory disease characterized by the activation and stress of various inflammatory cells, leading to the development of coronary artery disease and subsequently acute myocardial infarction (AMI). Among AMI cases, ST-segment elevation myocardial infarction (STEMI) is typically more severe than non-STEMI (NSTEMI). UL16-binding proteins (ULBPs), which are NKG2D ligands, can be expressed on the surface of stressed and activated cells, prompting these cells to generate microparticles (MPs). Consequently, MPs carrying ULBPs, particularly ULBP1 (ULBP1 MATERIALS AND

methodsWe recruited 58 AMI patients and 45 age-matched control subjects. Levels of ULBP1

resultsBoth ULBP1

conclusionElevated levels of ULBP1

Indexed as

BiomarkersCell-Derived MicroparticlesMyocardial InfarctionSeverity of Illness IndexAgedCase-Control StudiesFemaleGPI-Linked ProteinsHumansIntracellular Signaling Peptides and ProteinsMaleMiddle AgedRisk FactorsST Elevation Myocardial InfarctionBiomarkersGPI-Linked ProteinsIntracellular Signaling Peptides and ProteinsULBP1 protein, humanacute myocardial infarctionatherosclerosisinflammationmicroparticlesNKG2DULBP1+ MPsULBP1+ TMPs

Identifiers

PMID39477423
PMCPMC11535950

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.