Evidence map›Paper›PMID 39477856›Full record

ReviewHormones (Athens, Greece)2025

Clinical utility of anti-Müllerian hormone in female children and adolescents.

Effrosyni Birbas, Anastasia Vatopoulou, Theofilos Kanavos, Kyriakos Birmpas, Chara Skentou, Athanasios Zikopoulos, Fani Gkrozou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Hormones (Athens, Greece), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Effrosyni BirbasFaculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.ORCID http://orcid.org/0000-0002-5263-9207
Anastasia VatopoulouDepartment of Obstetrics and Gynecology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45500, Greece. anastasiavat@hotmail.com.ORCID http://orcid.org/0000-0001-5460-3323
Theofilos KanavosFaculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.ORCID http://orcid.org/0000-0002-4430-0588
Kyriakos BirmpasFaculty of Medicine, School of Health Sciences, University of Patras, Patras, 26504, Greece.ORCID http://orcid.org/0000-0001-6118-9706
Chara SkentouDepartment of Obstetrics and Gynecology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45500, Greece.
Athanasios ZikopoulosRoyal Devon and Exeter Hospital, Exeter, EX2 5DW, UK.
Fani GkrozouDepartment of Obstetrics and Gynecology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45500, Greece.ORCID http://orcid.org/0000-0001-7164-8603

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-Müllerian hormone (AMH) is a dimeric glycoprotein that belongs to the transforming growth factor beta superfamily and plays essential roles in sexual differentiation and folliculogenesis. In the male embryo, AMH is produced by the Sertoli cells and induces the involution of the Müllerian ducts. In females, AMH is predominately produced by the granulosa cells of growing preantral and small antral follicles and regulates follicular maturation. Many recent studies have highlighted the significant role of this hormone in the diagnostic approach to female children and adolescents with various disorders that affect ovarian development and function. AMH is considered a valuable diagnostic tool in the management of female pediatric patients with conditions such as polycystic ovary syndrome, precocious puberty, ovarian tumors, differences in sex development, and premature ovarian insufficiency. Standardization of AMH assays, internationally approved reference values based on age and pubertal stage, and widespread availability of the test could further upgrade the clinical utility of AMH, rendering it a valuable tool in the armamentarium of physicians involved in the care of female children and adolescents, and promote future research.

Indexed as

Anti-Mullerian HormoneOvarian NeoplasmsPolycystic Ovary SyndromePrimary Ovarian InsufficiencyPuberty, PrecociousAdolescentChildFemaleHumansAnti-Mullerian HormoneAdolescentsAMHAnti-Müllerian hormoneChildrenPCOSPolycystic ovary syndromePremature ovarian insufficiencyPuberty

Identifiers

PMID39477856

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.