Evidence map›Paper›PMID 39477860›Full record

ArticleArchives of osteoporosis2024

Sex-related differences in vitamin D testing in the Veneto Region, Italy: a retrospective analysis from 2005 to 2016.

Sandro Giannini, Annalisa Pitino, Stefania Sella, Maria Fusaro, Gaetano Paride Arcidiacono, Marco Onofrio Torres, Martina Zaninotto, Mercedes Gori, Andrea Aghi, Colin Gerard Egan and 3 more

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sandro GianniniClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Annalisa PitinoInstitute of Clinical Physiology (IFC), National Research Council (CNR), Rome, Italy.
Stefania SellaClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Maria FusaroClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy. dante.lucia11@gmail.com.
Gaetano Paride ArcidiaconoClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Marco Onofrio TorresClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Martina ZaninottoQI.Lab.Med, Spin-off of the University of Padova, Padua, Italy.
Mercedes GoriInstitute of Clinical Physiology (IFC), National Research Council (CNR), Rome, Italy.
Andrea AghiClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Colin Gerard EganCE Medical Writing SRLS, Pisa, Italy.
Paolo SimioniClinica Medica 1, Department of Medicine, University of Padova, Padua, Italy.
Giovanni TripepiInstitute of Clinical Physiology (IFC), National Research Council (CNR), Reggio Calabria, Italy.
Mario PlebaniQI.Lab.Med, Spin-off of the University of Padova, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective analysis was performed to evaluate the frequency of vitamin D blood testing in individuals from the Padua province, Veneto, Italy from 2005 to 2016. A significant increase in the frequency of vitamin D blood tests, particularly in females was observed and in individuals with severe vitamin D deficiency (Class I). PURPOSE: Vitamin D deficiency has been linked to negative health outcomes that extend beyond bone-related conditions. The frequency of vitamin D blood testing in residents from the Padua province, (Veneto, Italy) from 2005 to 2016 was evaluated.

methodsData were retrospectively retrieved from blood test databases (Laboratory Medicine Unit, Padua University Hospital) and information on number of vitamin D blood tests performed on residents from 2005 to 2016 was collected. Data were stratified by sex and ten birth cohorts from 1901 to 2016. Blood tests were classified into five vitamin D classes: I < 50 nmol/L, II 50-74.9 nmol/L, III 75-149 nmol/L, IV 150-250 nmol/L, and V > 250-1000 nmol/L. Blood test trends were analyzed as blood test rate and vitamin D class rate/resident population. Population analysis was analyzed by incidence rates and stratified by vitamin D class.

results293,013 vitamin D blood tests were conducted between 2005 and 2016 across 10 birth cohorts. Females accounted for 75% of tests and fewer were conducted in the youngest and oldest birth cohorts. Sex differences in vitamin D blood test frequency were observed; adjusted rates ranging from 1.7 to 35.6% for males and 8 to 81% for females from 2005 to 2016. Crude incidence rates (per 1000 from 2005 to 2016) varied from 1.5 to 10.8‰ for males and 7 to 19.4‰ for females. Crude blood test rates for vitamin D deficiency (Class I) increased from 1.1 to 9.9‰ in 2016 for males and 5 to 17.3‰ for females. Crude incidence rates (from 2005 to 2016) for Class I were 9.7-57.1‰ in males and 43.6-92.4‰ in females.

conclusionsThese findings highlight sex-related differences in vitamin D testing, providing valuable insight for healthcare planning.

Indexed as

Vitamin DVitamin D DeficiencyAdultAgedFemaleHumansIncidenceItalyMaleMiddle AgedRetrospective StudiesSex FactorsVitamin DOsteoporosisSexSupplementationVitamin D

Identifiers

PMID39477860
PMCPMC11525240

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.