Evidence mapPaperPMID 39479697Full record

ArticleFood science & nutrition2024

The effect of myo-inositol supplementation on AMPK/PI3K/AKT pathway and insulin resistance in patients with NAFLD.

Taha Aghajani, Sara Arefhosseini, Mehrangiz Ebrahimi-Mameghani, Reza Safaralizadeh

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In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Carob (Nutrients · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Taha AghajaniDepartment of Animal Biology, Faculty of Natural Sciences University of Tabriz Tabriz Iran.
Sara ArefhosseiniStudent Research Committee Tabriz University of Medical Sciences Tabriz Iran.
Mehrangiz Ebrahimi-MameghaniNutrition Research Center, Department of Biochemistry and Diet Therapy, Faculty of Nutrition and Food Sciences Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-0962-5571
Reza SafaralizadehDepartment of Animal Biology, Faculty of Natural Sciences University of Tabriz Tabriz Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin resistance (IR) is the pivotal pathological hit in non-alcoholic fatty liver disease (NAFLD). There is specific attention to combination/conjugated therapies for NAFLD management. As myo-inositol (MI) has been shown to improve IR in animal and human trials, this study aimed to investigate the influence of MI supplementation on glycemic response and IR through AMPK/PI3K/AKT signaling pathway in obese patients with NAFLD. This double-blinded placebo-controlled randomized clinical trial was conducted on 48 obese (BMI = 30-40 kg/m

Indexed as

gene expressioninsulin resistancemyo‐inositolnon‐alcoholic fatty liver disease

Identifiers

PMID39479697
PMCPMC11521746

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.