Evidence map›Paper›PMID 39479766›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2024

Whys and Wherefores of Coronary Arterial Positive Remodeling.

Carlotta Onnis, Renu Virmani, Anna Madra, Valentina Nardi, Rodrigo Salgado, Roberta Montisci, Riccardo Cau, Alberto Boi, Amir Lerman, Carlo N De Cecco and 2 more

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Relationship Between Carotid Artery Remodeling Characteristics and Early Carotid Atherosclerosis: An Ultrasonographic Multicenter Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carlotta OnnisDepartment of Radiology, Azienda Ospedaliero Universitaria, Cagliari, Italy (C.O., R.C., L.S.).ORCID 0000-0003-4466-5381
Renu VirmaniDepartment of Cardiovascular Pathology, CVPath Institute, Gaithersburg, MD (R.V., A.M.).ORCID 0000-0003-1879-0015
Anna MadraDepartment of Cardiovascular Pathology, CVPath Institute, Gaithersburg, MD (R.V., A.M.).ORCID 0000-0002-4122-9800
Valentina NardiDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (V.N., A.L.).ORCID 0000-0003-4601-0434
Rodrigo SalgadoDepartment of Radiology, Antwerp University Hospital and Antwerp University Lier, Belgium (R.S.).
Roberta MontisciClinical Cardiology, Department of Medical Science and Public Health, University of Cagliari, Italy (R.M.).ORCID 0000-0002-7218-6751
Riccardo CauDepartment of Radiology, Azienda Ospedaliero Universitaria, Cagliari, Italy (C.O., R.C., L.S.).ORCID 0000-0002-7910-1087
Alberto BoiDepartment of Cardiology, Azienda Ospedaliera Brotzu, Cagliari, Italy (A.B.).ORCID 0000-0001-5883-4778
Amir LermanDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (V.N., A.L.).ORCID 0000-0002-9446-5313
Carlo N De CeccoDivision of Cardiothoracic Imaging and Biomedical Informatics, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA (C.N.D.C.).ORCID 0000-0002-2956-3101
Peter LibbyDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (P.L.).ORCID 0000-0002-1502-502X
Luca SabaDepartment of Radiology, Azienda Ospedaliero Universitaria, Cagliari, Italy (C.O., R.C., L.S.).ORCID 0000-0003-2870-3771

Funding

Role of eosinophil cationic proteins in cardiac hypertrophyR01HL166538 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIBBY, PETER · 2023 to 2025
$2.1M
NHLBI NIH HHS R01 HL166538
6 · The paper itself

Abstract

Positive remodeling (PR) is an atherosclerotic plaque feature defined as an increase in arterial caliber at the level of an atheroma, in response to increasing plaque burden. The mechanisms that lead to its formation are incompletely understood, but its role in coronary atherosclerosis has major clinical implications. Indeed, plaques with PR have elevated risk of provoking acute cardiac events. Hence, PR figures among the high-risk plaque features that cardiac imaging studies should report. This review aims to provide an overview of the current literature on coronary PR. It outlines the pathophysiology of PR, the different techniques used to assess its presence, and the imaging findings associated to PR, on both noninvasive and invasive studies. This review also summarizes clinical observations, trials, and studies, focused on the impact of PR on clinical outcome.

Indexed as

Coronary Artery DiseaseCoronary VesselsPlaque, AtheroscleroticVascular RemodelingAnimalsHumansPredictive Value of TestsPrognosisatherosclerosiscardiac imaging techniquescoronary angiographycoronary vesselsdiagnostic imaging

Identifiers

PMID39479766
PMCPMC11594009

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.