Evidence map›Paper›PMID 39483022›Full record

ArticleAnimal bioscience2025

Milk traits characterization and association studies with DGAT1 polymorphisms in Bagnolese sheep.

Maria Giulia Pugliano, Gianfranco Cosenza, Emanuele D'Anza, Andrea Fulgione, Nicoletta Murru, Marika Di Paolo, Sara Albarella, Vincenzo Peretti, Francesca Ciotola

Abstract read
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Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Maria Giulia PuglianoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Gianfranco CosenzaDepartment of Agriculture, University of Napoli Federico II, Portici, Italy.
Emanuele D'AnzaDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Andrea FulgioneDepartment of Agriculture, University of Napoli Federico II, Portici, Italy.
Nicoletta MurruDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Marika Di PaoloDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Sara AlbarellaDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Vincenzo PerettiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Francesca CiotolaDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.

Funding

SAVEPEB Project: PSR Campania 2014-2020 G62C20000590007
6 · The paper itself

Abstract

objectiveThe Bagnolese sheep is an authochtonous dual-purpose breed (milk and meat) reared in the Campania region, whose milk is used to produce Pecorino Bagnolese cheese. Genetic information on this sheep is extremely limited, especially regarding genes affecting productions. The aim of this study was to investigate milk production traits in Bagnolese sheep and the variability of diacylglycerol acyltransferase 1 (DGAT1) gene and its effects on milk production.

methodsMilk quantity was recorded during the morning milking, while Kjeldahl and Gerber methods were used to assess protein and fat percentage (w/v) of collected milk samples. Two polymerase chain reaction-restriction fragment length polymorphism protocols using BamHI and MspI endonucleases for genotyping of g.5553C>T and g.8539C>T at DGAT1 locus, respectively, were set up.

resultsBagnolese sheep milk shows high fat and protein concentrations. Genotyping revealed a high frequency of the g.5553C and g.8539C alleles (0.56 and 0.95, respectively). The association study between the single nucleotide polymorphism (SNP) g.5553C>T and milk traits showed that animals with the CT genotype had a higher percentage of fat produced per milking than those with the CC and TT genotypes (p<0.01). Similar results were found for protein yield percentage, with CT individuals being more productive than CC individuals (p<0.01).

conclusionBagnolese sheep milk parameters found are associated with high yields in the resulting dairy products. CT genotype at the SNP g.5553 of DGAT1 has shown a positive association with fat and protein milk yield percentage suggesting it could be considered a marker to improve productions of this breed. Finally, the new genotyping techniques used for this study enable a cheap and reliable characterization of two DGAT1 SNPs in sheep.

Indexed as

Association AnalysesDGAT1Milk FatMilk ProteinOvis ariesSingle Nucleotide Polymorphisms (SNPs)

Identifiers

PMID39483022
PMCPMC12062812

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