Evidence map›Paper›PMID 39483245›Full record

ArticleJACS Au2024

Pyrimidine Azepine Targets the

Juliana Calit, Surendra K Prajapati, Ernest D Benavente, Jessica E Araújo, Bingbing Deng, Kazutoyo Miura, Yasmin Annunciato, Igor M R Moura, Miho Usui, Jansen F Medeiros and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Targeting Mitochondrial Function inInternational journal of molecular sciences · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Juliana CalitDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.
Surendra K PrajapatiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4712, United States.
Ernest D BenaventeLaboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht 3584 CS, The Netherlands.
Jessica E AraújoPlataforma de Produção e Infecção de Vetores da Malária-PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO 76812-245, Brazil.
Bingbing DengLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, United States.
Kazutoyo MiuraLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, United States.ORCID https://orcid.org/0000-0003-4455-2432
Yasmin AnnunciatoDepartment of Bioscience, Federal University of São Paulo, São Paulo, SP 04021-001, Brazil.
Igor M R MouraInstitute of Physics of São Carlos, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID https://orcid.org/0000-0003-3279-6894
Miho UsuiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4712, United States.
Jansen F MedeirosPlataforma de Produção e Infecção de Vetores da Malária-PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO 76812-245, Brazil.
Carolina H AndradeLabMol-Laboratory for Molecular Modeling and Drug Design-Faculty of Pharmacy, Federal University of Goias, Goiania, GO 74605-220, Brazil.ORCID https://orcid.org/0000-0003-0101-1492
Sabrina Silva-MendonçaLabMol-Laboratory for Molecular Modeling and Drug Design-Faculty of Pharmacy, Federal University of Goias, Goiania, GO 74605-220, Brazil.
Anton SimeonovDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20852, United States.
Richard T EastmanDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20852, United States.
Carole A LongLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, United States.
Maisa da Silva AraujoPlataforma de Produção e Infecção de Vetores da Malária-PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO 76812-245, Brazil.
Kim C WilliamsonDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4712, United States.ORCID https://orcid.org/0000-0003-2749-4082
Anna Caroline C AguiarDepartment of Bioscience, Federal University of São Paulo, São Paulo, SP 04021-001, Brazil.
Daniel Y BargieriDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.ORCID https://orcid.org/0000-0003-2564-3742

Funding

Gates Foundation INV-003970
6 · The paper itself

Abstract

Malaria control and elimination efforts would benefit from the identification and validation of new malaria chemotherapeutics. Recently, a transgenic

Identifiers

PMID39483245
PMCPMC11522906

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.