Evidence map›Paper›PMID 39483716›Full record

ArticleAsian journal of pharmaceutical sciences2024

Deep near infrared light-excited stable synergistic photodynamic and photothermal therapies based on P-IR890 nano-photosensitizer constructed

Dawei Jiang, Chao Chen, Peng Dai, Caiyan Li, Zhiyi Feng, Na Dong, Fenzan Wu, Junpeng Xu, Ping Wu, Liuxi Chu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dawei JiangAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Chao ChenInstitute for Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.
Peng DaiAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Caiyan LiAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Zhiyi FengAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Na DongAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Fenzan WuAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Junpeng XuAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Ping WuAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Liuxi ChuAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.
Shengcun LiSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China.
Xiaokun LiSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China.
Youjun YangState Key Laboratory of Bioreactor Engineering, Biomedical Nanotechnology Center, Shanghai Collaborative Innovation Center for Biomanufacturing Technology, School of Biotechnology, East China University of Science and Technology, Shanghai 200237, China.
Weian ZhangShanghai Key Laboratory of Functional Materials Chemistry, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China.
Zhouguang WangAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo 325300, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cyanine dyes represented by IR780 can achieve synergistic photodynamic therapy (PDT) and photothermal therapy (PTT) under the stimulation of near-infrared (NIR) light (commonly 808 nm). Unfortunately, the stability of NIR-excited cyanine dyes is not satisfactory. These cyanine dyes can be attacked by self-generated reactive oxygen species (ROS) during PDT processes, resulting in structural damage and rapid degradation, which is fatal for phototherapy. To address this issue, a novel non-cyanine dye (IR890) was elaborately designed and synthesized by our team. The maximum absorption wavelength of IR890 was located in the deep NIR region (

Indexed as

Deep near infrared lightIR780Non-cyanine dyePhotodynamic therapyPhotothermal therapy

Identifiers

PMID39483716
PMCPMC11525468

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.