Evidence map›Paper›PMID 39484364›Full record

SynthesisFrontiers in aging neuroscience2024

Systematic review and meta-analysis of the association between

Da Liu, Hongwei Zhang, Cao Liu, Jianyu Liu, Yan Liu, Na Bai, Qiang Zhou, Zhiyao Xu, Linyan Li, Hua Liu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Da Liu *Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Hongwei Zhang *Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Cao LiuChengdu Municipal Health Commission, Chengdu, China.
Jianyu LiuDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, China.
Yan LiuDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, China.
Na BaiDepartment of Neurology, The Sixth People's Hospital of Chengdu, Chengdu, China.
Qiang ZhouDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, China.
Zhiyao XuDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, China.
Linyan LiDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Hua LiuDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: The relationship between the Methods: Relevant studies were identified through comprehensive database searches, and the quality of each study was assessed using the Newcastle-Ottawa Scale (NOS). Allele and genotype frequencies were extracted from the included studies. The pooled odds ratios (OR) with corresponding 95% confidence intervals (CI) were calculated using random-effects or fixed-effects models. Multiple testing corrections were conducted using the false discovery rate (FDR) method. The Cochran Q statistic and I Results: A total of 36 studies, covering 21 polymorphisms and involving 31,809 AD cases and 44,994 controls, were included in this meta-analysis. NOS scores ranged from 7 to 9, indicating high-quality studies. A total of 11 SNPs (rs3764650, rs3752246, rs4147929, rs3752232, rs3752243, rs3764645, rs4147934, rs200538373, rs4147914, rs4147915, and rs115550680) in Conclusion: The available evidence suggests that specific Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier: CRD42024540539.

Indexed as

ABCA7Alzheimer’s diseasemeta-analysisSNPssystematic review

Identifiers

PMID39484364
PMCPMC11524920

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.